EMBOLIC PROTECTION SYSTEM

• US 20150112377A1
• Filed: 05/03/2013
• Published: 04/23/2015
• Est. Priority Date: 05/08/2012
• Status: Abandoned Application

• Current Assignee: Curators of the University of Missouri (University of Missouri)
• Original Assignee: Curators of the University of Missouri (University of Missouri)
• Inventors: Gopaldas, Raja R., Arnone, Joshua Clay, Rood, Kyle D., Mathews, Clint, Sweat, Charles Jr., Khushbu, Jain
• Application Number:
  US14/399,761
• Publication Number:
  US 20150112377A1
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2210/009 magnetic
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0039 differing in diameter

Abstract

A collapsible blood filtering aortic arch bridge comprising a dumbbell shaped chassis having a tubular waist, a first conical end, and a second conical end such that only a periphery of the first and second ends contact the intima of an aortic arch when the bridge is disposed and expanded within the aortic arch of a patient. The waist is flexible so that the bridge can bend to comply with the curvature of the aortic arch. The bridge additionally comprises a blood filtering sleeve disposed over an interior or an exterior of the chassis for filtering blood flowing through the bridge into aortic arch vessels of the patient when the bridge is disposed within the aortic arch. Furthermore, the bridge comprises a retrieval sleeve disposed over the exterior of the chassis for collapsing the bridge to a cylindrical form for retrieval of the bridge from the aortic arch.

Claims

1. An embolic protection system, said system comprising

a collapsible blood filtering aortic arch bridge structured and operable to bend to comply with the curvature of an aortic arch of a patient into which the bridge is disposable, the bridge comprising:

a chassis that is expandable and collapsible, the chassis structured to provide the bridge with a dumbbell-like shape when expanded having a tubular waist, a first conical end formed at a first end of the waist, and a second conical end formed at an opposing second end of the waist such that only a periphery of the first and second ends contact the intima of the aortic arch when the bridge is disposed and expanded within the aortic arch;

a blood filtering sleeve attached to the chassis, the blood filtering sleeve structured and operable to filter blood flowing through the bridge into aortic arch vessels of the patient when the bridge is disposed within the aortic arch; and

a retrieval sleeve disposed over an exterior of the chassis, the retrieval sleeve structured and operable to collapse the bridge to a cylindrical form for retrieval of the bridge from the aortic arch; and

a retrieval tool structured and operable to retrieve the bridge from disposition within the aortic arch, the retrieval tool comprising;

a multi-layer catheter;

a bridge coupling mechanism disposed at an end of the multi-layer catheter, the bridge coupling mechanism structured and operable to connect with the retrieval sleeve to retrieve the bridge from disposition within the aortic arch; and

a control handle connected to the catheter and structured and operable to control longitudinal movement of the retention wire and the outer sheath.

2. The system of claim 1, wherein the chassis is fabricated of shape memory material shape-set to provide a shape memory cage having the dumbbell-like shape that is transformable between the dumbbell-like shape and the cylindrical form.

3. The system of claim 1, wherein the blood filtering sleeve is fabricated of a biocompatible mesh that is a knitted mesh such that the blood filtering sleeve will elastically expand and contract longitudinally and not laterally when the bridge is collapsed from the to the cylindrical form for retrieval of the bridge.

4. The system of claim 1, wherein the retrieval sleeve is fabricated of a biocompatible mesh that is braided such that longitudinal force applied to an end of the sleeve will be converted to radial force utilized to collapse the bridge to the cylindrical form for retrieval of the bridge from disposition within the aortic arch.

5. The system of claim 4, wherein the retrieval sleeve comprises a plurality of retrieval strings connected to the retrieval sleeve and joined together at proximal ends, the retrieval strings structured and operable to connect with the bridge connector of the retrieval tool and transfer longitudinal force applied by the retrieval tool, via connect of the retrieval strings with the bridge connector, to the retrieval sleeve to collapse the bridge to the cylindrical form for retrieval of the bridge from disposition within the aortic arch.

6. The system of claim 5, wherein retrieval sleeve further comprises a magnetic button connected to the joined proximal ends of the retrieval strings, and the bridge connector of the retrieval tool comprises a magnetic receptacle magnetically connectable to the magnetic button to connect the retrieval tool with the retrieval sleeve for retrieval of the bridge from disposition within the aortic arch.

7. The system of claim 1, wherein the multi-layer catheter comprises:

a retention wire;

a flexible core concentrically disposed around the retention wire,

a flexible fixed tube concentrically disposed around the flexible core; and

a movable flexible outer sheath concentrically disposed around the flexible fixed tube.

8. The system of claim 7, wherein the bridge coupling mechanism comprises a bridge connector affixed to distal end of the retention wire, the bridge connector structured and operable to connect the catheter to the bridge.

9. The system of claim 8, wherein the bridge coupling mechanism further comprises a locking claw affixed to a distal end of the fixed tube and structured and operable to secure the connection of the bridge connector with the retrieval sleeve to retrieve the bridge from disposition within the aortic arch.

10. The system of claim 9, wherein the control handle comprises:

a housing and a catheter control module slideably disposed within the housing, the control module structured and operable to control the longitudinal movement of the retention wire and the outer sheath; and

a retention wire fixture structured and operable to retain the retention wire in a locked position wherein the locking claw secures the connection of the bridge connector with the retrieval sleeve.

11. A collapsible blood filtering aortic arch bridge, said bridge comprising:

an expandable and collapsible chassis structured to provide the bridge with a dumbbell-like shape when expanded having a tubular waist, a first conical end formed at a first end of the waist, and a second conical end formed at an opposing second end of the waist such that only a periphery of the first and second ends contact the intima of an aortic arch when the bridge is disposed and expanded within the aortic arch of a patient, the chassis structured and operable to bend to comply with the curvature of the aortic arch of the patient;

a blood filtering sleeve disposed over one of an interior or an exterior of the chassis, the blood filtering sleeve structured and operable to filter blood flowing through the bridge into aortic arch vessels of the patient when the bridge is disposed within the aortic arch; and

a retrieval sleeve disposed over the exterior of the chassis, the retrieval sleeve structured and operable to collapse the bridge to a cylindrical form for retrieval of the bridge from the aortic arch.

12. The bridge of claim 11, wherein the chassis is fabricated of shape memory material shape-set to provide a shape memory cage having the dumbbell-like shape that is transformable between the dumbbell-like shape and the cylindrical form.

13. The bridge of claim 11, wherein the blood filtering sleeve is fabricated of a biocompatible mesh that is a knitted mesh such that the blood filtering sleeve will elastically expand and contract longitudinally and not laterally when the bridge is collapsed from the to the cylindrical form for retrieval of the bridge.

14. The bridge of claim 11, wherein the retrieval sleeve is fabricated of a biocompatible mesh that is braided such that longitudinal force applied to an end of the sleeve will be converted to radial force utilized to collapse the bridge to the cylindrical form for retrieval of the bridge from disposition within the aortic arch.

15. The bridge of claim 14, wherein the retrieval sleeve comprises a plurality of retrieval strings connected to the retrieval sleeve and joined together at proximal ends, the retrieval strings structured and operable to connect with a bridge retrieval tool and transfer longitudinal force applied by the retrieval tool to the retrieval sleeve to collapse the bridge to the cylindrical form for retrieval of the bridge from disposition within the aortic arch.

16. The bridge of claim 15, wherein retrieval sleeve further comprises a magnetic button connected to the joined proximal ends of the retrieval strings for magnetic connection to the retrieval tool for retrieval of the bridge from disposition within the aortic arch.

17. The bridge of claim 11, wherein the first conical end of the chassis has a larger outside diameter than the second conical end such that the bridge conforms to the physical shape and structure of the aortic arch.

18. A collapsible blood filtering aortic arch bridge, said bridge comprising:

an expandable and collapsible chassis fabricated of shape memory material and structured to provide the bridge with a dumbbell-like shape when expanded having a tubular waist, a first conical end formed at a first end of the waist, and a second conical end formed at an opposing second end of the waist such that only a periphery of the first and second ends contact the intima of an aortic arch when the bridge is disposed and expanded within the aortic arch of a patient, the first conical having a larger outside diameter than the second conical end such that the bridge conforms to the physical shape and structure of the aortic arch, and the waist being flexible so that the bridge can bend to comply with the curvature of the aortic arch of the patient;

a blood filtering sleeve disposed over one of an interior or an exterior of the chassis, the blood filtering sleeve structured and operable to filter blood flowing through the bridge into aortic arch vessels of the patient when the bridge is disposed within the aortic arch; and

a retrieval sleeve disposed over the exterior of the chassis, the retrieval sleeve structured and operable to collapse the bridge to a cylindrical form for retrieval of the bridge from the aortic arch, the retrieval sleeve comprises a plurality of retrieval strings connected to the retrieval sleeve and joined together at proximal ends, the retrieval strings structured and operable to connect with a bridge retrieval tool and transfer longitudinal force applied by the retrieval tool to the retrieval sleeve to collapse the bridge to the cylindrical form for retrieval of the bridge from disposition within the aortic arch.

19. The bridge of claim 18, wherein the blood filtering sleeve is fabricated of a biocompatible mesh that is a knitted mesh such that the blood filtering sleeve will elastically expand and contract longitudinally and not laterally when the bridge is collapsed from the to the cylindrical form for retrieval of the bridge.

20. The bridge of claim 18, wherein the retrieval sleeve is fabricated of a biocompatible mesh that is braided such that longitudinal force applied to an end of the sleeve will be converted to radial force utilized to collapse the bridge to the cylindrical form for retrieval of the bridge from disposition within the aortic arch.

21. The bridge of claim 18, wherein retrieval sleeve further comprises a magnetic button connected to the joined proximal ends of the retrieval strings for magnetic connection to the retrieval tool for retrieval of the bridge from disposition within the aortic arch.

22. A retrieval tool structured and operable to retrieve an inner tubular organ (ITO) device disposed within an interior of a tubular organ of a patient, said tool comprising:

a multi-layer catheter comprising;

a flexible retention wire;

a flexible core concentrically disposed around the retention wire,

a flexible fixed tube concentrically disposed around the flexible core; and

a flexible movable outer sheath concentrically disposed around the fixed tube;

an ITO device coupling mechanism disposed at a distal end of the multi-layer catheter, the ITO device coupling mechanism structured and operable to connect with the ITO device to retrieve the ITO device from disposition within the interior of a tubular organ of the patient; and

a control handle connected to the catheter and structured and operable to control longitudinal movement of the retention wire and the outer sheath.

23. The system of claim 22, wherein the ITO device coupling mechanism comprises a bridge connector affixed to distal end of the retention wire, the bridge connector structured and operable to connect the catheter to the bridge.

24. The system of claim 23, wherein the ITO device coupling mechanism comprises a locking claw affixed to a distal end of the fixed tube and structured and operable to secure the connection of the bridge connector with the retrieval sleeve to retrieve the bridge from disposition within the aortic arch.

25. The system of claim 24, wherein the control handle comprises a housing and a catheter control module slideably disposed within the housing, the control module structured and operable to control the longitudinal movement of the retention wire and the outer sheath.

26. The system of claim 25, wherein the control handle comprises a retention wire fixture structured and operable to retain the retention wire in a locked position wherein the locking claw secures the connection of the bridge connector with the retrieval sleeve.