TIME-RESOLVED PRE-TREATMENT PORTAL DOSIMETRY SYSTEMS, DEVICES, AND METHODS
First Claim
Patent Images
1. A time-dependent pre-treatment dosimetric evaluation method for a radiation therapy device, comprising:
- generating a sequence of portal dose images based on images continuously acquired during beam delivery according to a treatment plan, each portal dose image in the sequence corresponding to a measured dose delivered at a predetermined time interval of the treatment plan;
for each predetermined time interval, comparing the generated portal dose image with a corresponding predicted portal dose image; and
evaluating dose delivery based on the comparison.
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Abstract
Systems, devices, and methods for pre-treatment verification of radiation dose delivery in arc-based radiation therapy devices using a time-dependent gamma evaluation method.
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Citations
36 Claims
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1. A time-dependent pre-treatment dosimetric evaluation method for a radiation therapy device, comprising:
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generating a sequence of portal dose images based on images continuously acquired during beam delivery according to a treatment plan, each portal dose image in the sequence corresponding to a measured dose delivered at a predetermined time interval of the treatment plan; for each predetermined time interval, comparing the generated portal dose image with a corresponding predicted portal dose image; and evaluating dose delivery based on the comparison. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method for verifying quantities of interest of a radiation beam in an arc-based radiation therapy device, comprising:
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continuously acquiring portal images during a continuous arc beam delivery using the electronic portal imaging device (EPID); converting the acquired portal images into absolute portal dose images using a dosimetric calibration model; resampling the absolute portal dose images into respective time divisions corresponding to a treatment plan'"'"'s control points (CPs) to obtain a sequence of measured portal dose images, each measured portal dose image in the sequence corresponding to a respective (CP); comparing each of the measured portal dose images in the sequence with corresponding predicted portal dose images using a 4D time-dependent gamma evaluation function; and determining dose delivery errors based on the comparison by assessing the amount of voxels that change over time with a gamma metric exceeding unity. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23)
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24. A system for verifying quantities of interest of a radiation beam in an arc-based radiation therapy device including a gantry, comprising:
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a portal imaging device configured to measure incident radiation dose from predetermined radiation fields corresponding to an arc segment of the gantry and to generate a series of two-dimensional (2D) absolute portal dose images using a calibration model; and a processing device operably connected to the portal dose imaging device and configured to store the series of 2D absolute portal dose images in a first 4D array having spatial locations and time of delivery of the predetermined radiation fields as dimensions, the processing device being further configured to store a series of predicted 2D portal dose images in a second 4D array having spatial locations and time of delivery of predicted radiation fields as dimensions; wherein the processing device is further configured to compare points in the first 4D array with corresponding points in the second 4D array using a 4D gamma evaluation method, the gamma evaluation method including dose differences, spatial differences, and time differences between corresponding points in the first and second 4D arrays as parameters, and wherein errors in the quantities of interest are determined based on the comparison. - View Dependent Claims (25, 26, 27, 28)
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29. A non-transitory computer-readable storage medium upon which is embodied a sequence of programmed instructions for verifying quantities of interest of a radiation beam in a system including an arc-based radiation therapy device including a gantry and a computer processing system which executes the sequence of programmed instructions embodied on the computer-readable storage medium to cause the computer processing system to perform the steps of:
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continuously acquiring portal images during a continuous arc beam delivery using an electronic portal imaging device (EPID); converting the acquired portal images into absolute portal dose images using a dosimetric calibration model; resampling the absolute portal dose images into respective time divisions corresponding to a treatment plan'"'"'s control points (CPs) to obtain a sequence of measured portal dose images, each measured portal dose image in the sequence corresponding to a respective (CP); comparing each of the measured portal dose images in the sequence with corresponding predicted portal dose images using a time-dependent gamma evaluation function; and determine dose delivery errors based on the comparison by assessing the amount of voxels that change over time exceeding unity. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36)
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Specification