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Cyclosporine-Containing Non-Irritative Nanoemulsion Ophthalmic Composition

  • US 20150125494A1
  • Filed: 01/22/2013
  • Published: 05/07/2015
  • Est. Priority Date: 04/30/2012
  • Status: Active Grant
First Claim
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1. A nanoemulsion ophthalmic composition, comprising:

  • 0.01 to 1 wt % of cyclosporine;

    0.5 to 9.79 wt % of polyethoxylated castor oil or polyethoxylated hydrogenated castor oil; and

    90 to 99.29 wt % of phosphate buffer,wherein the composition uses the polyethoxylated castor oil or polyethoxylated hydrogenated castor oil as a solubilizer of the cyclosporine, so that a separate oil or emulsifier is unnecessary, and the composition is prepared by simple mixing.

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