CLINICAL OUTCOME TRACKING AND ANALYSIS

• US 20150127385A1
• Filed: 01/12/2015
• Published: 05/07/2015
• Est. Priority Date: 10/08/2013
• Status: Active Grant

• Current Assignee: COTA, Inc.
• Original Assignee: COTA, Inc.
• Inventors: Pecora, Andrew L.
• Granted Patent: US 9,378,531 B2
• Time in Patent Office: Days
• US Class Current: 705/3
• CPC Class Codes: G06F 16/285 Clustering or classification
• CPC Class Codes: G06F 16/9024 Graphs; Linked lists G06F16/9027 takes precedence
• CPC Class Codes: G06F 16/9535 Search customisation based on user profiles and personalisation
• CPC Class Codes: G06Q 10/0637 Strategic management or analysis, e.g. setting a goal or target of an organisation; Planning actions based on goals; Analysis or evaluation of effectiveness of goals
• CPC Class Codes: G06Q 10/10 Office automation; Time management
• CPC Class Codes: G06Q 30/0201 Market modelling; Market analysis; Collecting market data
• CPC Class Codes: G16H 10/20 for electronic clinical trials or questionnaires
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 40/20 for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: G16H 70/20 relating to practices or guidelines

Abstract

The described invention provides a system and method for clinical outcome tracking and analysis. The clinical outcome tracking and analysis comprises sorting, outcome tracking, quality of life metrics, toxicity to therapy and cost of care. The system and method includes receiving one or more parameters. Exemplary parameters for sorting include sex, age, ethnicity, comorbidities, tobacco use, source of insurance, medical record number, primary care physician, referring physician, hospital, approved service vendors, disease-specific clinical molecular phenotype, therapy intent, stage of therapy, biomarkers, and cost of care. A plurality of patient medical records are sorted, by a clinical outcome tracking and analysis module executed by a processor, to provide a set of patient medical records satisfying the one or more parameters. A nodal address, indicating one or more variables, is applied to the sorted set of patient medical records to determine a clinically relevant set of patient medical records as the sorted set of patient medical records satisfying the one or more variables. The clinically relevant set of patient medical records is analyzed. A communication is transmitted based on the analyzing to a user to effect treatment, to monitor performance, or to reduce at least one of treatment variability, waste or inefficiency while delivering on intended outcome.

Claims

1. A method for clinical outcome tracking and analysis, comprising:

receiving one or more parameters;

sorting a plurality of patient medical records to provide a sorted set of patient medical records satisfying the one or more parameters;

applying a nodal address, indicating one or more variables, to the sorted set of patient medical records to determine a clinically relevant set of patient medical records as the sorted set of patient medical records satisfying the one or more variables;

analyzing the clinically relevant set of patient medical records; and

transmitting a communication based on the analyzing, wherein the transmitting is to a user to effect treatment, to monitor performance, or to reduce at least one of treatment variability, waste or inefficiency while delivering on intended clinical outcome.

2. The method as recited in claim 1, wherein the clinical outcome tracking and analysis comprises sorting, outcome tracking, quality of life metrics, toxicity to therapy and cost of care.

3. The method as recited in claim 2, wherein the parameters for sorting comprise sex, age, ethnicity, comorbidities, tobacco use, source of insurance, medical record number, primary care physician, referring physician, hospital, approved service vendors, disease-specific clinical molecular phenotype, therapy intent, stage of therapy, biomarkers, and cost of care.

4. The method as recited in claim 1, wherein the nodal address is represented as a plurality of strings of digits, each of the plurality of strings of digits representing one of the one or more variables.

5. The method as recited in claim 4, wherein the one or more variables include the disease-specific clinical molecular phenotype and a string of digits representing the phenotype is determined based on a directed graph.

6. The method as recited in claim 1, wherein the nodal address is associated with one or more bundles of predetermined patient care services for treatment of the disease.

7. The method as recited in claim 1, wherein analyzing comprises:

tracking clinical outcomes of one or more patients associated with a disease; and

updating records of the one or more patients with the clinical outcomes of the one or more patients.

8. The method as recited in claim 7, wherein the clinical outcomes comprise at least one of survival, response metrics, quality of life metrics, incidence of drug toxicity, severity of drug toxicity, delivered dose intensity, drugs received, drug interval, drug duration, cost of care, and death.

9. The method as recited in claim 1, wherein analyzing comprises:

comparing tracked clinical outcomes between patients in the set of patient medical records.

10. The method as recited in claim 1, wherein analyzing comprises:

identifying a specific patient as a candidate for a specific drug.

11. The method as recited in claim 1, wherein analyzing comprises:

comparing clinical outcomes between patients based on treatment, cost, or a combination thereof in the set of patient medical records.

12. The method as recited in claim 1, wherein analyzing comprises:

comparing a therapy to a quality of life.

13. The method as recited in claim 1, wherein transmitting a communication comprises:

sending at least a portion of the analyzed set of patient medical records to a client device for display.

14. The method as recited in claim 1, wherein transmitting a communication comprises:

transmitting, in response to a trigger, an alert to a client device, the trigger comprising at least one of diagnosis, progression, dose change, drug change, toxicity, trending towards variance from a desired outcome, and a specific time.

15. The method as recited in claim 1, wherein analyzing comprises:

comparing outcome performance of a medical professional treating a disease to outcome performance of an aggregate of medical professionals treating the disease.

16. The method as recited in claim 1, wherein the method minimizes biological variability of clinical outcome.

17. An apparatus for clinical outcome tracking and analysis comprising:

a processor; and

a memory to store computer program instructions, the computer program instructions when executed on the processor cause the processor to perform operations comprising;

receiving one or more parameters;

sorting a plurality of patient medical records to provide a set of patient medical records satisfying the one or more parameters;

applying a nodal address, indicating one or more variables, to the sorted set of patient medical records to determine a clinically relevant set of patient medical records as the sorted set of patient medical records satisfying the one or more variables;

analyzing the clinically relevant set of patient medical records; and

transmitting a communication based on the analyzing,

wherein the transmitting is to a user to effect treatment, to monitor performance, or to reduce at least one of treatment variability, waste or inefficiency while delivering on intended outcome.

18. The apparatus as recited in claim 17, wherein the clinical outcome tracking and analysis comprises sorting, outcome tracking, quality of life metrics, toxicity to therapy and cost of care.

19. The apparatus as recited in claim 17, wherein the parameters for sorting comprise sex, age, ethnicity, comorbidities, tobacco use, source of insurance, medical record number, primary care physician, referring physician, hospital, approved service vendors, disease-specific clinical molecular phenotype, therapy intent, stage of therapy, biomarkers and cost of care.

20. The apparatus as recited in claim 17, wherein the nodal address is represented as a plurality of strings of digits, each of the plurality of strings of digits representing one of the one or more variables.

21. The apparatus as recited in claim 20, wherein the one or more variables include the disease-specific clinical molecular phenotype and a string of digits representing the phenotype is determined based on a directed graph.

22. The apparatus as recited in claim 17, wherein the nodal address is associated with one or more bundles of predetermined patient care services for treatment of the disease.

23. A computer readable medium storing computer program instructions for clinical outcome tracking and analysis which, when executed on a processor, cause the processor to perform operations comprising:

receiving one or more parameters;

sorting a plurality of patient medical records to provide a set of patient medical records satisfying the one or more parameters;

applying a nodal address, indicating one or more variables, to the sorted set of patient medical records to determine a clinically relevant set of patient medical records as the sorted set of patient medical records satisfying the one or more variables;

analyzing the clinically relevant set of patient medical records; and

transmitting a communication based on the analyzing,

wherein the transmitting is to a user to effect treatment, to monitor performance, or to reduce at least one of treatment variability, waste or inefficiency while delivering on intended outcome.

24. The computer readable medium as recited in claim 23, wherein the clinical outcome tracking and analysis comprises sorting, outcome tracking, quality of life metrics, toxicity to therapy and cost of care.

25. The computer readable medium as recited in claim 23, wherein the parameters comprise sex, age, ethnicity, comorbidities, tobacco use, source of insurance, medical record number, primary care physician, referring physician, hospital, approved service vendors, disease-specific clinical molecular phenotype, therapy intent, stage of therapy, biomarkers and cost of care.

26. The computer readable medium as recited in claim 23, wherein analyzing comprises one or more of:

(a) tracking clinical outcomes of one or more patients associated with a disease and updating records of the one or more patients with the clinical outcomes;

(b) comparing clinical outcomes between patients based on treatment, cost, or a combination thereof in the set of patient medical records;

(c) comparing tracked clinical outcomes between patients in the set of patient medical records;

(d) identifying a specific patient as a candidate for a specific drug;

(e) comparing clinical outcome between patients based on treatment, cost, or a combination thereof in the set of patient medical records;

(f) comparing a therapy to a quality of life.

27. The computer readable medium as recited in claim 23, wherein the clinical outcomes comprise at least one of survival, response metrics, quality of life metrics, incidence of drug toxicity, severity of drug toxicity, delivered dose intensity, drugs received, drug interval, drug duration, cost of care, and death.

28. The computer readable medium as recited in claim 23, wherein transmitting a communication comprises:

sending at least a portion of the analyzed set of patient medical records to a client device for display.

29. The computer readable medium as recited in claim 23, wherein transmitting a communication comprises:

transmitting, in response to a trigger, an alert to a client device, the trigger comprising at least one of diagnosis, progression, dose change, drug change, toxicity, trending towards variance from a desired outcome, and a specific time.