GALVANICALLY ASSISTED ATTACHMENT OF MEDICAL DEVICES TO THROMBUS

• US 20150133990A1
• Filed: 11/13/2014
• Published: 05/14/2015
• Est. Priority Date: 11/13/2013
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: DAVIDSON, James
• Granted Patent: US 9,795,400 B2
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/00831 Material properties
• CPC Class Codes: A61B 2017/00929 isolating electrical current
• CPC Class Codes: A61B 2017/22001 Angioplasty, e.g. PCTA
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2230/0023 triangular
• CPC Class Codes: A61F 2250/0043 differing in electric properties, e.g. in electrical conductivity, in galvanic properties
• CPC Class Codes: A61N 1/378 Electrical supply

Abstract

A medical device configured to perform an endovascular therapy can include an elongate manipulation member and an intervention member. The elongate manipulation member can include a distal end portion. The intervention member can include a proximal end portion and a mesh. The proximal end portion can be coupled with the distal end portion of the elongate manipulation member. The mesh can have a plurality of cells in a tubular configuration and being compressible to a collapsed configuration for delivery to an endovascular treatment site through a catheter and being self-expandable from the collapsed configuration to an expanded configuration. The mesh can include an anodic metal and a cathodic metal. The anodic metal and the cathodic metal can each form a fraction of a total surface area of the mesh.

Claims

1. A medical device configured to perform an endovascular therapy, the device comprising:

an elongate manipulation member comprising a distal end portion; and

an intervention member comprising a proximal end portion and a mesh, the proximal end portion being coupled with the distal end portion of the elongate manipulation member, the mesh having a plurality of cells in a tubular configuration and being compressible to a collapsed configuration for delivery to an endovascular treatment site through a catheter and being self-expandable from the collapsed configuration to an expanded configuration, and the mesh comprising an anodic metal and a cathodic metal, and the anodic metal and the cathodic metal each forming a fraction of a total surface area of the mesh.

2. The medical device of claim 1, wherein the fraction of the surface area formed by the anodic metal is located primarily at an internal aspect of the mesh.

3. The medical device of claim 1, wherein less than 50% of the surface area formed by the anodic metal is located at an external surface of the mesh.

4. The medical device of claim 1, wherein 35% to 85% of the surface area of the mesh is formed by the anodic metal.

5. The medical device of claim 1, wherein an outwardly facing surface of the mesh is formed substantially only by the cathodic metal.

6. The medical device of claim 1, wherein the fraction of the surface area formed by the anodic metal comprises a plurality of discrete portions of the anodic metal.

7. The medical device of claim 1, wherein the fraction of the surface area formed by the anodic metal is contiguous.

8. The medical device of claim 1, wherein an engagement portion of the surface area is configured to engage an interior surface of a catheter during delivery of the medical device through a lumen of the catheter, and an average coefficient of friction of the engagement portion is less than an average coefficient of friction of the surface area excluding the engagement portion.

9. The medical device of claim 1, wherein an engagement portion of the surface area is configured to engage an interior surface of a catheter during delivery of the medical device through a lumen of the catheter, and substantially none of the engagement portion is formed by the anodic metal.

10. The medical device of claim 1, wherein the anodic metal is in direct contact with the cathodic metal.

11. The medical device of claim 1, wherein at least a portion of the anodic metal has a thickness of at least 2 μ

m.

12. The medical device of claim 1, wherein the anodic metal comprises magnesium and the cathodic metal comprises nickel and titanium.

13. The medical device of claim 1, wherein the mesh is rolled in the collapsed configuration such that a first portion and a second portion of the mesh are overlapped in at least one radial direction with a surface area of the first portion contacting a surface area of the second portion, and each of the surface area of the first portion and the surface area of the second portion comprises substantially no anodic metal.

14. The medical device of claim 1, further comprising a temporary cover material that encapsulates at least a portion of the anodic metal.

15. The medical device of claim 14, wherein the temporary cover material is erodible, dissolvable, degradable or absorbable in vivo.

16. The medical device of claim 15, wherein the temporary cover material encapsulates substantially all of the anodic metal.

17. A medical device configured to perform an endovascular therapy, the device comprising:

an elongate manipulation member comprising a distal end portion; and

an intervention member comprising a proximal end portion and a mesh, the proximal end portion being coupled with the distal end portion of the elongate manipulation member, the mesh having a plurality of cells in a tubular configuration and being compressible to a collapsed configuration for delivery to an endovascular treatment site through a catheter and being self-expandable from the collapsed configuration to an expanded configuration, and the mesh comprising means for galvanically assisting internal attachment of the mesh to thrombus.

18. The medical device of claim 17, wherein the means for galvanically assisting attachment of the mesh to thrombus comprises an anodic metal and a cathodic metal.

19. The medical device of claim 17, wherein the anodic metal comprises magnesium and the cathodic metal comprises nickel and titanium.