Patient Signal Analysis Based on Actiniform Segmentation

• US 20150164429A1
• Filed: 10/22/2014
• Published: 06/18/2015
• Est. Priority Date: 12/16/2013
• Status: Active Grant

• Current Assignee: PixArt Imaging Incorporated
• Original Assignee: Siemens Medical Solutions USA Incorporated (Siemens AG)
• Inventors: Zhang, Hongxuan
• Granted Patent: US 9,277,889 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 5/0036 including treatment, e.g., using an implantable medical device, ablating, ventilating
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: A61B 5/7235 Details of waveform analysis A61B5/349 takes precedence
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/3904 External heart defibrillators [EHD]
• CPC Class Codes: A61N 1/3906 characterised by the form of the shockwave

Abstract

Disclosed herein is a framework for facilitating patient signal analysis. In accordance with one aspect, actiniform segmentation is performed on patient signal data waveform based on an actiniform shape. The actiniform shape is centered at a peak of the waveform and includes connection lines extending from the peak to key time points of the patient signal data waveform. Actiniform parameters may be extracted from the segmented patient signal data waveform. Additionally, one or more actiniform ratios may be determined based on the actiniform parameters to monitor changes in the patient signal data waveform.

Claims

1. A system for patient signal analysis, comprising:

a patient monitor configured to acquire a patient signal data waveform from a patient;

a medical treatment device configured to provide treatment to the patient; and

a computer system communicatively coupled to the patient monitor and the medical treatment device, wherein the computer system includes

a non-transitory memory device for storing computer readable program code, and

a processor in communication with the memory device, the processor being operative with the computer readable program code to perform steps including

performing actiniform segmentation on the patient signal data waveform based on an actiniform shape centered at a peak of the waveform,

extracting actiniform parameters from the segmented patient signal data waveform,

determining one or more actiniform ratios based on the actiniform parameters,

determining control parameters based on the one or more actiniform ratios, and

controlling the medical treatment device by applying the control parameters.

2. The system of claim 1 wherein the medical treatment device comprises a pacing device, an ablator, a cardioverter or a defibrillator.

3. The system of claim 1 wherein the actiniform shape is centered at an R wave peak of the patient signal data waveform.

4. The system of claim 1 wherein the actiniform shape comprises connection lines extending from the peak to key time points of the patient signal data waveform.

5. The system of claim 4 wherein at least one of the key time points is defined by a P wave, Q wave, R wave, S wave or T wave.

6. The system of claim 4 wherein at least one of the key time points is defined at a time point before a P wave or after a T wave.

7. The system of claim 1 wherein the patient monitor comprises a multi-channel intra-cardiac electrographic lead system.

8. A computer-implemented method of patient signal analysis, comprising:

performing, by a processor, actiniform segmentation on patient signal data waveform based on an actiniform shape centered at a peak of the waveform, wherein the actiniform shape includes connection lines extending from the peak to key time points of the patient signal data waveform;

extracting, by the processor, actiniform parameters from the segmented patient signal data waveform; and

determining, by the processor, one or more actiniform ratios based on the actiniform parameters to monitor changes in the patient signal data waveform.

9. The method of claim 8 wherein performing the actiniform segmentation comprises:

detecting an R wave peak in the patient signal data waveform;

defining the actiniform shape centered at the R wave peak; and

segmenting the patient signal data waveform into multiple different portions using the actiniform shape.

10. The method of claim 8 wherein at least one of the key time points is defined by a P wave, Q wave, R wave, S wave or T wave.

11. The method of claim 8 wherein at least one of the key time points is defined at a time point before a P wave and/or after a T wave.

12. The method of claim 8 wherein the actiniform parameters comprise angles, distances or areas.

13. The method of claim 8 wherein the one or more actiniform ratios comprise a unilateral actiniform ratio.

14. The method of claim 13 wherein the unilateral actiniform ratio comprises an actiniform shape ratio.

15. The method of claim 13 wherein the unilateral actiniform ratio comprises an actiniform distance ratio.

16. The method of claim 13 wherein the unilateral actiniform ratio comprises an actiniform area ratio.

17. The method of claim 13 wherein the unilateral actiniform ratio comprises an actiniform energy ratio.

18. The method of claim 8 wherein the one or more actiniform ratios comprise a unilateral actiniform integrating ratio that includes a weighted sum of different unilateral actiniform ratios.

19. The method of claim 8 wherein the one or more actiniform ratios comprise a single actiniform index variation.

20. The method of claim 8 wherein the one or more actiniform ratios comprise a single actiniform ratio variation.

21. The method of claim 8 wherein the one or more actiniform ratios comprise a bilateral actiniform ratio.

22. The method of claim 21 wherein the bilateral actiniform ratio comprises a cross actiniform index variation.

23. The method of claim 21 wherein the bilateral actiniform ratio comprises a cross actiniform ratio variation.

24. The method of claim 8 further comprises mapping the one or more actiniform ratios to corresponding sites of a heart.

25. A non-transitory computer readable medium embodying a program of instructions executable by machine to perform steps for cardiac function characterization, the steps comprising:

detecting an R wave peak of a patient signal data waveform;

performing actiniform segmentation on the patient signal data waveform based on an actiniform shape centered at the R wave peak, wherein the actiniform shape includes connection lines extending from the R wave peak to key time points of the patient signal data waveform;

extracting actiniform parameters from the segmented patient signal data waveform; and

determining one or more actiniform ratios based on the actiniform parameters to monitor changes in the patient signal data waveform.