Neferine and the use thereof in treating Huntington disease
First Claim
Patent Images
1. A method of treating neurodegenerative disorder comprising administering an effective amount of an alkaloid to a subject in need thereof, wherein said alkaloid is a bisbenzylisoquinline alkaloid isolated from the traditional Chinese medicinal herb Nelumbo nucifera, wherein said bisbenzylisoquinline alkaloid is neferine.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention discloses a method of treating neurodegenerative disorder comprising administering an effective amount of an alkaloid which is a bisbenzylisoquinline alkaloid isolated from the traditional Chinese medicinal herb Nelumbo nucifera. The pharmaceutical composition thereof for treating Huntington'"'"'s disease is also disclosed.
1 Citation
8 Claims
- 1. A method of treating neurodegenerative disorder comprising administering an effective amount of an alkaloid to a subject in need thereof, wherein said alkaloid is a bisbenzylisoquinline alkaloid isolated from the traditional Chinese medicinal herb Nelumbo nucifera, wherein said bisbenzylisoquinline alkaloid is neferine.
- 4. Use of an alkaloid in inducing autophagy in neurodegenerative cells, wherein said alkaloid is a bisbenzylisoquinline alkaloid isolated from the traditional Chinese medicinal herb Nelumbo nucifera, wherein said bisbenzylisoquinline alkaloid is neferine.
- 7. A pharmaceutical composition for treating neurodegenerative disorder comprising an effective amount of an alkaloid, wherein said alkaloid is a bisbenzylisoquinline alkaloid isolated from the traditional Chinese medicinal herb Nelumbo nucifera, wherein said bisbenzylisoquinline alkaloid is neferine.
Specification