MOBILE DEVICE SYSTEM FOR MEASUREMENT OF CARDIOVASCULAR HEALTH

• US 20150182132A1
• Filed: 02/04/2013
• Published: 07/02/2015
• Est. Priority Date: 08/10/2012
• Status: Abandoned Application

• Current Assignee: CNV Systems Limited
• Original Assignee: CNV Systems Limited
• Inventors: Harris, Paul Ronald, Li, Ji Feng
• Application Number:
  US14/420,375
• Publication Number:
  US 20150182132A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor
• CPC Class Codes: A61B 5/6823 Trunk, e.g., chest, back, abdomen, hip
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence

Abstract

A system that continuously monitors cardiovascular health using an electrocardiography (ECG) source synchronized to an optical (PPG) source, without requiring invasive techniques or ongoing, large-scale external scanning procedures. The system includes an ECG signal source with electrodes contacting the skin, which generates a first set of information, and a mobile device having a camera which acts as a PPG signal source that generates a second set of information. Together with the mobile device'"'"'s processor, configured to receive and process the first and second sets of information, from which the time differential of the heart beat pulmonary pressure wave can be calculated, continuous data related to cardiovascular health markers such as arterial stiffness can be determined. Variations of the ECG source may include a chest strap, a plug-in adaptor for the mobile device, or electrodes built into the mobile device.

Claims

1. A system for monitoring cardiovascular health comprising:

a) an electrode-based module, comprising at least two electrodes which contact skin, to generate a first set of data measuring a target heart beat;

b) a mobile device, held in a hand, comprising;

i) an optical module, comprising a camera, to generate a second set of data measuring a pulse wave created by the same target heart beat corresponding to the first set of data;

ii) a processor, in communication with both the electrode-based module and the optical module, that receives the first and second sets of data and calculates at least one cardiovascular health value using the data; and

iii) a wireless transceiver, operably connected to the processor, for data exchange.

2. The system of claim 1, wherein the cardiovascular health value is at least one of arterial stiffness, blood pressure, heart rate, pulse transit time, and pulse wave velocity.

3. The system of claim 1, wherein the mobile device is one of a smartphone, cell phone, tablet, personal digital assistant (PDA), handheld console, digital camera, and digital camcorder.

4. The system of claim 1, wherein the wireless transceiver utilizes Bluetooth technology.

5. The system of claim 1, wherein the electrode-based module is a chest-worn electrocardiographic source with a wireless transmitter.

6. The system of claim 1, wherein the electrode-based module is a plug-in ECG adaptor for the mobile device, said adaptor comprising at least two surface, contact electrodes and a means to plug into the mobile device.

7. The system of claim 1, wherein the electrode-based module comprises at least two surface, contact electrodes integrated with the mobile device.

8. The system of claim 1, wherein there are two electrode-based modules, one of which is a chest-worn electrocardiographic source with a wireless transmitter, and the other of which comprises surface, contact electrodes connected to the mobile device.

9. The system of claim 1, wherein the optical module is a photoplethysmographic source.

10. The system of claim 1, wherein the mobile device further comprises an accelerometer in communication with the processor.

11. An ECG adaptor, for a mobile device, comprising:

a. a housing;

b. at least two contact electrodes on the surface of the housing;

c. a processor within the housing;

d. an analog-to-digital converter within the housing which converts the analog signal from the contact electrodes into a digital signal that is conveyed to the processor; and

e. a means to plug into the mobile device and allow the adaptor'"'"'s processor to communicate with the mobile device'"'"'s processor.

12. The adaptor of claim 11, wherein the mobile device is one of a smartphone, cell phone, tablet, personal digital assistant (PDA), handheld console, digital camera, and digital camcorder.

13. The adaptor of claim 11, wherein the adaptor is plugged into the main bus port of the mobile device.

14. A method of monitoring at least one cardiovascular health marker over time comprising the following steps, in interchangeable order where possible:

a. obtaining an ECG signal for a target heart beat to generate a first set of data;

b. obtaining a PPG signal for a pulse wave from the same target heart beat, using a mobile device having a camera which functions as a PPG source, to generate a second set of data;

c. transmitting the first and second sets of data to the mobile device'"'"'s processor;

d. calculating at least one cardiovascular health marker with the processor, using the first and second sets of data;

e. monitoring at least one cardiovascular health marker continuously over time.

15. The method of claim 14, wherein the cardiovascular health marker is at least one of arterial stiffness, blood pressure, heart rate, pulse transit time, and pulse wave velocity.

16. The method of claim 14, wherein the ECG signal is obtained via a wireless ECG source strapped around a user'"'"'s chest.

17. The method of claim 14, wherein the ECG signal is obtained via ECG contact electrodes on the mobile device.

18. The method of claim 14, wherein the ECG signal is obtained via ECG contact electrodes on an adaptor connected to the mobile device.

19. The method of claim 14, further comprising a step wherein a second ECG signal for a target heart beat is obtained to generate a third set of data that is also transmitted to the processor and may be used to calibrate the first and second sets of data, with a synchronized system of two ECG and one PPG sources.

20. The method of claim 14, further comprising a step wherein streams of prolonged uninterrupted data measurements of at least 24 hours for each data stream, are collected across independent sequential date ranges and compared with each other to determine rate of change in at least one cardiovascular health marker.