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METHODS AND DEVICES FOR REMOTE ISCHEMIC CONDITIONING VIA PARTIAL LIMB OCCLUSION

  • US 20150190301A1
  • Filed: 03/18/2015
  • Published: 07/09/2015
  • Est. Priority Date: 06/23/2009
  • Status: Active Grant
First Claim
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1. A device for delivery of remote ischemic conditioning treatment to a subject, said device comprising:

  • a cuff configured for placement over a limb of the subject, said cuff is further configured to at least partially reduce blood flow in said limb upon inflation thereof;

    a controller operably connected to said cuff, said controller is configured upon activation to deliver said remote ischemic conditioning treatment by performing a plurality of remote ischemic conditioning treatment cycles, each treatment cycle comprising;

    a period of cuff inflation when said controller is causing said cuff to be inflated to and maintained at or above a pressure sufficient to cause at least a partial reduction of blood flow in said limb to produce an ischemic stress therein for at least about one minute, anda period of cuff deflation when said controller is causing said cuff to deflate so as to increase blood flow in said limb and relieve said ischemic stress,wherein said ischemic stress is sufficient to cause said remote ischemic conditioning treatment, said controller is further configured to avoid complete occlusion of said limb by said cuff lasting more than about one minute during at least one of said treatment cycles.

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