ANTICANCER THERAPY
2 Assignments
0 Petitions
Accused Products
Abstract
A subject afflicted with a cancer or precancerous condition is treated by administering an agent that increases expression of somatostatin receptors, and a cytotoxic recognition ligand. In an alternative embodiment, somatostatin analogs, which are radiolabeled are used to treat cancer or precancerous conditions.
4 Citations
60 Claims
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1-47. -47. (canceled)
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48. A method of treating a somatostatin receptor expressing cancerous tumor in a patient in need, the method comprising administering to said patient an effective amount of a composition comprising chelate-linked peptide analog of somatostatin comprising a radionuclide, wherein said peptide analog of somatostatin is Tyr3-Octreotide, said chelate is 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) and said radionuclide is the α
- particle emitter 213Bi (213Bi-DOTATOC), in a pharmaceutically acceptable carrier, optionally in combination with an additional anti-cancer compound.
- View Dependent Claims (49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60)
Specification