PERFUSION ASSESSMENT MULTI-MODALITY OPTICAL MEDICAL DEVICE

• US 20150198797A1
• Filed: 07/05/2013
• Published: 07/16/2015
• Est. Priority Date: 07/10/2012
• Status: Active Grant

• Current Assignee: Stryker Corporation
• Original Assignee: Aïmago SA (Stryker Corporation)
• Inventors: Andre, Marc, Friedrich, Michael
• Granted Patent: US 10,101,571 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0035 adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/7425 Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image geometric transforms for image registration G06T3/14; enhancement using image fusion G06T5/50; algorithms for registration of images G06T7/30
• CPC Class Codes: A61B 90/361 Image-producing devices, e.g. surgical cameras
• CPC Class Codes: G02B 21/16 adapted for ultraviolet illumination ; Fluorescence microscopes G02B21/0076 takes precedence
• CPC Class Codes: G02B 21/365 Control or image processing arrangements for digital or video microscopes G02B21/361, G02B21/362 take precedence
• CPC Class Codes: G02B 2207/113 Fluorescence

Abstract

A perfusion assessment multi-modality optical medical device comprising a white light image sensor (320) and optical system configured to image a body area of interest (130, 340), a coherent light source (330) for illuminating said body area of interest 110 with wavelength of 760-810 nm, an optical coherence imaging (OCI) image sensor (310) detecting the fluctuations of the backscattered light (302) near the illumination wavelength from at least part of said illuminated body area of interest (340), a fluorescence image sensor (315) to detect the fluorescence signal at higher wavelength than the illumination wavelength from at least part of said illuminated body area of interest (340), a screen (115, 210) to show the results from the modalities, all previous items being included in a single movable unit (200) which furthermore comprises a processing unit (105, 110) to calculate perfusion map from the OCI image sensor (310) using LDI or LSI algorithms, wherein said white light image sensor (320), said OCI image sensor (310) and said fluorescence image sensor (315), at least partially, use a common optical path (610).

Claims

1. A perfusion assessment multi-modality optical medical device comprising:

a white light image sensor and optical system configured to image a body area of interest;

a coherent light source for illuminating said body area of interest with wavelength of 760-810 nm;

an OCI image sensor that detects fluctuations of backscattered light near the illumination wavelength from at least part of said illuminated body area of interest;

a fluorescence image sensor to detect the fluorescence signal at higher wavelength than the illumination wavelength from at least part of said illuminated body area interest; and

a screen to show the results from the multi-modalities, wherein

the white light image sensor and optical system, the coherent light source, the OCI image sensor, the fluorescence image sensor, and the screen are included in a single movable unit, the single movable unit further including a processing unit to calculate perfusion map from the OCI image sensor using LDI or LSI algorithms, and

said white light image sensor, said OCI image sensor, and said fluorescence image sensor, at least partially, use a common optical path.

2. The device according to claim 1, wherein said OCI image sensor and said fluorescence image sensor are a single image sensor.

3. The device according to claim 1, wherein the white light image sensor is configured such that a body area of interest can be shown with at least 1.5×

magnification.

4. The device according to claim 1, further comprising detecting means for the position and orientation of the device head in relation to a patient.

5. The device according to claim 4, further comprising a processing unit to render and show stored images and/or metadata related to the currently visualized body area.

6. The device according to claim 1, further comprising a general processing unit to combine the results of two or more of the multi-modalities.

7. The device according to claim 6, wherein the general processing unit is used to calculate reliability information by comparing the OCI and fluorescence maps.

8. The device according to claim 6, wherein the general processing unit is used to separate microvascular perfusion from large vessels.

9. The device according to claim 6, wherein the general processing unit is used to generate an overlay image from at least two Modalities

10. The device according to claim 1, further comprising an auto-focus system for the white light image wherein the focus point is automatically detected by locating the point on the screen which is focused by the user'"'"'s eye.

11. The device according to claim 1, further comprising a microphone and a processing unit to record and analyze voice and to recognize voice commands, such commands being used to control the device.

12. The device according to claim 1, further comprising a usage based billing which stores at least the used modality and usage time, and where this usage information is transferred to a billing server via Internet.