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MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE

  • US 20150218559A1
  • Filed: 04/16/2015
  • Published: 08/06/2015
  • Est. Priority Date: 03/21/2003
  • Status: Abandoned Application
First Claim
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1. An isolated antisense oligonucleotide of 15 to 80 nucleotides in length wherein said oligonucleotide is capable of binding to a sequence internal to exon 55 of the human dystrophin pre-mRNA and inducing skipping of said exon, said oligonucleotide comprising a modification.

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