PHOTOACOUSTIC MONITORING TECHNIQUE WITH NOISE REDUCTION
First Claim
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1. A monitor, comprising:
- a memory storing instructions for;
receiving a signal from an acoustic detector configured to detect a photoacoustic effect from light emitted into a patient'"'"'s tissue, wherein the signal is representative of an indicator dilution;
dividing the signal into a plurality of blocks, wherein each block includes a same number of epochs;
arranging the respective epochs within each block of the plurality of blocks in an ensemble arrangement;
identifying a region of each respective epoch within each block that corresponds to a blood vessel response;
calculating an indicator dilution curve based on the identified regions of the epochs;
identifying a signal region of the indicator dilution curve;
extracting one or more features from the signal region of the indicator dilution curve; and
determining a physiological parameter based on the one or more features; and
a processor configured to execute the instructions.
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Abstract
Various methods and systems for photoacoustic patient monitoring are provided. A photoacoustic system includes a light emitting component that emits one or more wavelengths of light into an interrogation region of a patient and an acoustic detector that detects acoustic energy generated by the interrogation region of the patient in response to the emitted light. The system also includes techniques to remove noise from the signal generated by the acoustic detector.
21 Citations
20 Claims
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1. A monitor, comprising:
a memory storing instructions for; receiving a signal from an acoustic detector configured to detect a photoacoustic effect from light emitted into a patient'"'"'s tissue, wherein the signal is representative of an indicator dilution; dividing the signal into a plurality of blocks, wherein each block includes a same number of epochs; arranging the respective epochs within each block of the plurality of blocks in an ensemble arrangement; identifying a region of each respective epoch within each block that corresponds to a blood vessel response; calculating an indicator dilution curve based on the identified regions of the epochs; identifying a signal region of the indicator dilution curve; extracting one or more features from the signal region of the indicator dilution curve; and determining a physiological parameter based on the one or more features; and a processor configured to execute the instructions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for determining a physiological parameter of a patient, comprising:
using a processor for; receiving a signal from an acoustic detector configured to detect a photoacoustic effect from light emitted into a patient'"'"'s tissue, wherein the signal is representative of an indicator dilution; dividing the signal into a plurality of blocks, wherein each block includes a same number of epochs; arranging the respective epochs within each block of the plurality of blocks in an ensemble arrangement; identifying a region of each respective epoch that corresponds to a blood vessel response utilizing an ensemble-averaged envelope calculated for each block of the plurality of blocks based on the respective epochs within each block; calculating an indicator dilution curve based on the identified regions of the epochs; identifying a signal region of the indicator dilution curve; extracting one or more features from the signal region of the indicator dilution curve; and determining a physiological parameter based on the one or more features utilizing ridge regression. - View Dependent Claims (18)
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19. A non-transitory computer-readable medium having computer executable code stored thereon, the code comprising instructions for:
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receiving a signal from an acoustic detector configured to detect a photoacoustic effect from light emitted into a patient'"'"'s tissue, wherein the signal is representative of an indicator dilution; dividing the signal into a plurality of blocks, wherein each block includes a same number of epochs; identifying a region of each respective epoch within each block that corresponds to a blood vessel response; calculating an indicator dilution curve based on the identified regions of the epochs; identifying a signal region of the indicator dilution curve; extracting one or more features from the signal region of the indicator dilution curve; and determining a physiological parameter based on the one or more features utilizing ridge regression. - View Dependent Claims (20)
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Specification