SYSTEMS AND METHODS FOR DELIVERING DRUGS TO A TREATMENT SITE

• US 20150238736A1
• Filed: 02/27/2015
• Published: 08/27/2015
• Est. Priority Date: 02/27/2014
• Status: Abandoned Application

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Zeng, Hongxia, Chen, Yen-Lane, Kangas, Steven L.
• Application Number:
  US14/634,085
• Publication Number:
  US 20150238736A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1059 having different inflatable sections mainly depending on the response to the inflation pressure, e.g. due to different material properties with different compartments A61M2025/1072
• CPC Class Codes: A61M 2025/1061 having separate inflations tubes, e.g. coaxial tubes or tubes otherwise arranged apart from the catheter tube
• CPC Class Codes: A61M 2025/1072 having balloons with two or more compartments
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

A catheter system includes a catheter having a first balloon and a second balloon. The first balloon is longitudinally offset from the second balloon along the length of the catheter. The first and second balloons both have expanded and unexpanded states. The second balloon has a drug coating. The catheter system has a first configuration, a second configuration, and a third configuration. In the first configuration, the first balloon is in the unexpanded state and the second balloon is in the unexpanded state. In the second configuration, the first balloon is in the expanded state and the second balloon is in the unexpanded state. In the third configuration, the first balloon is in the expanded state and the second balloon is in the expanded state.

Claims

1. A catheter system having a first configuration, a second configuration, and a third configuration, the catheter system comprising:

a catheter having a first balloon and a second balloon, the first balloon longitudinally offset from the second balloon along the length of the catheter, the first and second balloons both having expanded and unexpanded states, wherein at least one of the first balloon and the second balloon has a drug coating;

in the first configuration, the first balloon is in the unexpanded state and the second balloon is in the unexpanded state;

in the second configuration, the first balloon is in the expanded state and the second balloon is in the unexpanded state; and

in the third configuration, the first balloon is in the expanded state and the second balloon is in the expanded state.

2. The catheter system of claim 1 defining a first inflation lumen in fluid communication with the first balloon and a second inflation lumen in fluid communication with the second balloon.

3. The catheter system of claim 1 defining an inflation lumen in fluid communication with both the first and second balloons.

4. The catheter system of claim 1, wherein the first balloon has a first inflation pressure in the expanded state and the second balloon has a second inflation pressure in the expanded state, the second inflation pressure being greater than the first inflation pressure.

5. The catheter system of claim 1, wherein the second balloon has a larger volume than the first balloon in the third configuration.

6. A catheter system having a first configuration, a second configuration, and a third configuration, the catheter system comprising:

a catheter having an inflatable balloon, the inflatable balloon having a first section and a second section, the second section longitudinally offset from the first section;

the first and second sections both having expanded and unexpanded states, the second section having a drug coating, the first section being free of any drug coating;

in the first configuration, the first section is in the unexpanded state and the second section is in the unexpanded state;

in the second configuration, the first section is in the expanded state and the second section is in the unexpanded state; and

in the third configuration, the first section is in the expanded state and the second section is in the expanded state.

7. The catheter system of claim 6 defining an inflation lumen in fluid communication with both the first and second sections.

8. The catheter system of claim 6, wherein the first section is formed from a different material than the second section.

9. The catheter system of claim 8, wherein the material forming the second section is more stiff than the material forming the first section.

10. The catheter system of claim 8, wherein the material forming the second section has a greater tensile modulus than the material forming the first section.

11. The catheter system of claim 6, wherein, in the third configuration, the first section and second section are separated by a region of reduced cross-section, the region of reduced cross-section having a smaller cross-sectional area than the first section and the second section.

12. The catheter system of claim 6, wherein the second section has a larger volume than the first section.

13. The catheter system of claim 6, wherein the second section is longer than the first section.

14. The catheter system of claim 6, wherein the second section is distal to the first section.

15. The catheter system of claim 6, wherein the first section is distal to the second section.

16. A method of deploying a catheter system within a bodily lumen having a lumen wall, the method comprising:

providing a catheter having a first balloon and a second balloon, the first balloon longitudinally offset from the second balloon, the second balloon has thereon a drug coating comprising a drug, the first balloon being free of any drug coating;

deploying the first balloon within the bodily lumen upstream of the second balloon, wherein deployment of the first balloon stagnates the fluid within the bodily lumen downstream of the first balloon;

deploying the second balloon within the bodily lumen in the stagnated fluid; and

emitting the drug;

transferring the drug to the lumen wall;

deflating the first and second balloons; and

removing the catheter from the bodily lumen.

17. The method of claim 16, wherein the catheter system includes a first inflation lumen and the step of deploying the first balloon within the bodily lumen includes conveying an inflation fluid through the first inflation lumen into the first balloon.

18. The method of claim 17, wherein the catheter system includes a second inflation lumen and the step of deploying the second balloon within the bodily lumen includes conveying an inflation fluid through the second inflation lumen into the second balloon.

19. The method of claim 16, wherein the step of deploying the first balloon within the bodily lumen includes conveying a saline solution into the first balloon.

20. The method of claim 17, wherein the step of deploying the second balloon within the bodily lumen includes conveying a saline solution into the second balloon.