GLASS FOR PHARMACEUTICAL CONTAINERS, GLASS TUBE FOR PHARMACEUTICAL CONTAINERS OBTAINED THEREFROM, METHOD FOR PRODUCING PHARMACEUTICAL CONTAINER, AND PHARMACEUTICAL CONTAINER

• US 20150246846A1
• Filed: 07/17/2013
• Published: 09/03/2015
• Est. Priority Date: 07/18/2012
• Status: Abandoned Application

• Current Assignee: Nippon Electric Glass Company Limited
• Original Assignee: Nippon Electric Glass Company Limited
• Inventors: Choju, Ken, Kawamoto, Kosuke, Murata, Takashi, Yamamoto, Kazuyuki
• Application Number:
  US14/413,023
• Publication Number:
  US 20150246846A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: B65D 1/40 Details of walls other container details B65D23/00, B65D25/00
• CPC Class Codes: C03C 21/002 to perform ion-exchange between alkali ions C03C21/005 takes precedence
• CPC Class Codes: C03C 3/087 containing calcium oxide, e.g. common sheet or container glass
• CPC Class Codes: C03C 3/091 containing aluminium
• CPC Class Codes: C03C 3/11 containing halogen or nitrogen
• CPC Class Codes: Y10T 428/131 Glass, ceramic, or sintered, fused, fired, or calcined metal oxide or metal carbide containing [e.g., porcelain, brick, cement, etc.]

Abstract

Provided is a glass for pharmaceutical containers which, after formed into final products such as ampoules, vials, pre-filled syringes, and cartridges, renders the containers capable of being sufficiently chemically strengthened, and a glass tube formed therefrom. The glass for pharmaceutical containers of the present invention comprises, in terms of mol %, 50-80% of SiO₂, 5-30% of Al₂O₃, 0-2% of Li₂O, and 5-25% of Na₂O.

Claims

1. A glass for pharmaceutical containers which has a glass composition comprising, in terms of mol %, 50-80% of SiO₂, 5-30% of Al₂O₃, 0-2% of Li₂O, and 5-25% of Na₂O.

2. The glass for pharmaceutical containers according to claim 1, which has a glass composition comprising, in terms of mol %, 50-80% of SiO₂, 5-30% of Al₂O₃, 0-2% of Li₂O, 5-25% of Na₂O, 0-10% of MgO, and 0-10% of CaO.

3. The glass for pharmaceutical containers according to claim 1, which has a glass composition comprising, in terms of mol %, 50-80% of SiO₂, 5-30% of Al₂O₃, 0-2% of Li₂O, 5-25% of Na₂O, 0-10% of MgO, 0-10% of CaO, and 1-10% of B₂O₃.

4. The glass for pharmaceutical containers according to claim 1, which, when subjected to an ion-exchange treatment in 440°

C. KNO₃ molten salt, forms a compression stress layer that has a value of compression stress of 300 MPa or higher and a thickness of 10 μ

m or larger.

5. The glass for pharmaceutical containers according to claim 1, which has a liquidus viscosity of 10^4.0 dPa·

s or higher.

6. The glass for pharmaceutical containers according to claim 1, which has a coefficient of thermal expansion of 100×

10<sup>−

7</sup>/°

C. or less in the temperature range of 30-380°

C.

7. A glass tube for pharmaceutical containers which is formed from the glass according to claim 1.

8. The glass tube for pharmaceutical containers according to claim 7, which is formed by the Danner method.

9. The glass tube for pharmaceutical containers according to claim 7, which has an outer diameter of 5-50 mm and a thickness of 0.3-2 mm.

10. A method for producing a pharmaceutical container, the method comprising the following steps:

step a);

a step in which the glass tube for pharmaceutical containers according to claim 7 is processed into a pharmaceutical container having a desired shape;

step b);

a step in which the pharmaceutical container obtained by processing in step a) is subjected to a strengthening treatment.

11. A pharmaceutical container produced by the production method according to claim 10.

13. A glass tube for pharmaceutical containers which is formed from the glass according to claim 3.

15. The glass tube for pharmaceutical containers according to claim 7, which is formed by the Danner method and which has an outer diameter of 5-50 mm and a thickness of 0.3-2 mm.

16. The glass tube for pharmaceutical containers according to claim 13, which is formed by the Danner method and which has an outer diameter of 5-50 mm and a thickness of 0.3-2 mm.

18. A method for producing a pharmaceutical container, the method comprising the following steps:

step a);

a step in which the glass tube for pharmaceutical containers according to claim 13 is processed into a pharmaceutical container having a desired shape;

step b);

a step in which the pharmaceutical container obtained by processing in step a) is subjected to a strengthening treatment.

20. A pharmaceutical container produced by the production method according to claim 18.

12. A glass for pharmaceutical containers:

which has a glass composition comprising, in terms of mol %, 50-80% of SiO₂, 5-30% of Al₂O₃, 0-2% of Li₂O, 5-25% of Na₂O, 0-10% of MgO, 0-10% of CaO, and 1-10% of B₂O₃;

which, when subjected to an ion-exchange treatment in 440°

C. KNO₃ molten salt, forms a compression stress layer that has a value of compression stress of 300 MPa or higher and a thickness of 10 μ

m or large;

which has a liquidus viscosity of 10^4.0 dPa·

s or higher; and

which has a coefficient of thermal expansion of 100×

10<sup>−

7</sup>/°

C. or less in the temperature range of 30-380°

C.

14. A glass tube for pharmaceutical containers which is formed from the glass according to claim 12.

17. The glass tube for pharmaceutical containers according to claim 14, which is formed by the Danner method and which has an outer diameter of 5-50 mm and a thickness of 0.3-2 mm.

19. A method for producing a pharmaceutical container, the method comprising the following steps:

step a);

a step in which the glass tube for pharmaceutical containers according to claim 17 is processed into a pharmaceutical container having a desired shape;

step b);

a step in which the pharmaceutical container obtained by processing in step a) is subjected to a strengthening treatment.

21. A pharmaceutical container produced by the production method according to claim 19.