Methods, Devices, Kits and Compositions for Detecting Roundworm, Whipworm, and Hookworm
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Accused Products
Abstract
Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
5 Citations
91 Claims
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1-59. -59. (canceled)
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60. A kit for detection of one or more roundworm coproantigens, one or more whipworm coproantigens and/or one or more hookworm coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a whipworm or hookworm coproantigen; (b) a second antibody capable of specifically binding a whipworm coproantigen, but not a roundworm or hookworm coproantigen; and (c) a third antibody capable of specifically binding a hookworm coproantigen, but not a whipworm or roundworm coproantigen, and (d) one or more reagents suitable for the detection of the one or more coproantigens. - View Dependent Claims (61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74)
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75. A kit for detection of the presence or absence of one or more helminthic coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a whipworm coproantigen; (b) a second antibody capable of specifically binding a whipworm coproantigen, but not a roundworm coproantigen; and (c) one or more reagents suitable for the detection of the one or more helminthic coproantigens. - View Dependent Claims (78, 79, 80, 81, 83, 84, 85, 87, 88, 89, 90, 91)
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76. A kit for detection of the presence or absence of one or more helminthic coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a hookworm coproantigen; (b) a second antibody capable of specifically binding a hookworm coproantigen, but not a roundworm coproantigen; and (c) one or more reagents suitable for the detection of the one or more helminthic coproantigens. - View Dependent Claims (82, 86)
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77. A kit for detection of the presence or absence of one or more helminthic coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a whipworm coproantigen, but not a hookworm coproantigen; (b) a second antibody capable of specifically binding a hookworm coproantigen, but not a whipworm coproantigen; and (c) one or more reagents suitable for the detection of the one or more helminthic coproantigens.
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Specification