BIOLOGICAL STATE ASSESSMENT DEVICE AND PROGRAM THEREFOR

• US 20150297126A1
• Filed: 06/21/2012
• Published: 10/22/2015
• Est. Priority Date: 06/21/2012
• Status: Active Grant

• Current Assignee: Hitachi, Ltd.
• Original Assignee: Hitachi, Ltd.
• Inventors: KIGUCHI, Masashi, ATSUMORI, Hirokazu
• Granted Patent: US 9,706,955 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2505/09 Rehabilitation or training
• CPC Class Codes: A61B 2560/0475 Special features of memory means, e.g. removable memory cards
• CPC Class Codes: A61B 2562/0238 Optical sensor arrangements for performing transmission measurements on body tissue
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/14553 specially adapted for cerebral tissue
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7435 Displaying user selection data, e.g. icons in a graphical user interface
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: G06N 5/04 Inference or reasoning models

Abstract

Provided is a biological state assessment device for assessing biological state, such as mood or emotions, using non-invasive biophotonic measurement technology. The present invention includes a light irradiation unit (1041), a light-receiving unit (1061), and an inputting means (112). A subject (800) is presented with a plurality of different problems (first problem, second problem), and a biological signal in the interior of the subject is calculated from the intensity of light received by the light-receiving unit (1061). Subjective information about the subject is accepted by the inputting means (112). The difference is calculated between the subjective information and the relative value of the biological signal of the measurement point for the first problem and the biological signal of the measurement point for the second problem, and the result is displayed.

Claims

1. A biological state assessment device comprising:

one or a plurality of irradiation units configured to irradiate a subject with light;

one or a plurality of light receiving units configured to detect light transmitted through or reflected off the subject;

a display unit configured to display a plurality of different tasks to the subject;

an operating unit configured to show the task on the display unit and calculate a biological signal in an inside of the subject from intensity of light received at the light receiving unit;

a storage unit configured to store the biological signal; and

an input unit configured to accept an input of subjective information about the subject,

wherein the operating unit calculates and displays a difference between a relative value of biological signals reflecting the plurality of the tasks and the subjective information.

2. The biological state assessment device according to claim 1,

wherein:

there is a plurality of measurement points formed of a combination of the irradiation unit and the light receiving unit; and

the relative value is calculated from a biological signal for a first task at a first measurement point and a biological signal for a second task at a second measurement point, and a difference between the relative value and the subjective information is calculated and displayed.

3. The biological state assessment device according to claim 2,

wherein the first task is a spatial working memory task and the second task is a verbal working memory task.

4. The biological state assessment device according to claim 3,

wherein the relative value is calculated by an equation below:

Mood_index=(Act_—

2−

Act_—

1)/(|Act_—

2|+|Act_—

1|)

where, Act_1 is defined as a brain activity value for a spatial working memory task, and Act_2 is defined as a brain activity value for a verbal working memory task.

5. The biological state assessment device according to claim 1,

wherein:

the storage unit is enabled to memorize the relative value and the subjective information, which are acquired; and

the operating unit displays a relative value and subjective information in a past on the display unit together with the relative value and the subjective information.

6. The biological state assessment device according to claim 5,

wherein the operating unit displays changes over time in the relative value and subjective information.

7. The biological state assessment device according to claim 5,

wherein the operating unit further calculates a correlation coefficient between the relative value and the subjective information including a measured result acquired in a past and displays the correlation coefficient on the display unit.

8. The biological state assessment device according to claim 5,

wherein the operating unit further calculates a correlation coefficient for a specific number of times between the relative value and the subjective information including a measured result acquired in a past, and displays changes over time in the correlation coefficient.

9. A program that causes a biophotonic measurement device to operate as a biological state assessment device, the biophotonic measurement device including:

one or a plurality of irradiation units configured to irradiate a subject with light;

one or a plurality of light receiving units configured to detect light transmitted through or reflected off the subject;

a display unit configured to display a plurality of different tasks to the subject;

an operating unit configured to show the task on the display unit and calculate a biological signal in an inside of the subject from intensity of light received at the light receiving unit;

a storage unit configured to store the biological signal; and

an input unit, the program causing the operating unit formed of a computer to function to calculate and display a difference between a relative value of biological signals with respect to the plurality of the tasks and subjective information about the subject inputted from the input unit.

10. The program according to claim 9,

wherein:

there is a plurality of measurement points formed of a combination of the irradiation unit and the light receiving unit; and

the relative value is calculated from a biological signal for a first task at a first measurement point and a biological signal for a second task at a second measurement point, and a difference between the relative value and the subjective information is calculated and displayed.

11. The program according to claim 10,

wherein the first task is a spatial working memory task and the second task is a verbal working memory task.

12. The program according to claim 11,

wherein the relative value is calculated by an equation below:

Mood_index=(Act_—

2−

Act_—

1)/(|Act_—

2|+|Act_—

1|)

where, Act_1 is defined as a brain activity value for a spatial working memory task, and Act_2 is defined as a brain activity value for a verbal working memory task.

13. The program according to claim 9,

wherein the operating unit is caused to function to further display a relative value and subjective information in a past on the display unit together with the relative value and the subjective information.

14. The program according to claim 13,

wherein the operating unit is caused to further function to calculate a correlation coefficient between the relative value and the subjective information including a measured result acquired in a past and display the correlation coefficient on the display unit.

15. The program according to claim 13,

wherein the operating unit is caused to further function to calculate a correlation coefficient for a specific number of times between the relative value and the subjective information including a measured result acquired in a past, and display changes over time in the correlation coefficient.