GLUCOSE SENSOR EMPLOYING SEMICONDUCTOR NANOELECTRONIC DEVICE
First Claim
Patent Images
1. A glucose sensor, comprising:
- a nanoelectronic device having a control surface functionalized with a glucose-reactive substance; and
a fluid interface structure configured to allow contact between the control surface and a bodily fluid.
1 Assignment
0 Petitions
Accused Products
Abstract
A glucose sensor employs a programmable glucose sensor array of a relatively large number of nanoelectronic devices (e.g. semiconductor field-effect devices) having control surfaces functionalized with a glucose-reactive substance and generating sensing signals indicative of sensed glucose level of a bodily fluid. The devices arc divided into sub-sets sequentially enabled over successive intervals to achieve overall sensor lifetime many times longer than the lifetime of any single device in operation.
-
Citations
20 Claims
-
1. A glucose sensor, comprising:
-
a nanoelectronic device having a control surface functionalized with a glucose-reactive substance; and a fluid interface structure configured to allow contact between the control surface and a bodily fluid. - View Dependent Claims (2, 3, 4, 5, 6, 14, 15)
-
-
7. A glucose sensor, comprising:
-
an array of nanoelectronic devices having respective control surfaces functionalized with a glucose-reactive substance which chemically interacts with glucose to affect electrical conduction characteristics of the nanoelectronic devices, the array being configured to allow for intimate contact between the control surfaces and a glucose-carrying bodily fluid, the array of nanoelectronic devices being logically organized into a plurality of individually operable subsets of the nanoelectronic devices, each subset being operable for only a limited period before operational degradation due to interaction between the bodily fluid and operating nanoelectronic sensors of the subset; device selection circuitry operative in response to control inputs to enable electrical sensing operation of a selected one of the subsets of the nanoelectronic devices to generate respective sensing output signals while simultaneously disabling such electrical sensing operation of remaining ones of the subsets of the nanoelectronic devices; and control circuitry operative to generate the control signals so as to serially enable electrical operation of successive ones of the subsets of the nanoelectronic devices over an extended period generally equal to the product of the limited period and the number of the subsets of the nanoelectronic devices. - View Dependent Claims (8, 9, 10, 11, 12, 13)
-
-
16. A method of continual, extended sensing of glucose level of a glucose-carrying bodily fluid, comprising:
-
bringing the glucose-carrying bodily fluid into intimate contact with control surfaces of an array of nanoelectronic devices of a glucose sensor, the control surfaces being functionalized with a glucose-reactive substance which chemically interacts with glucose to affect electrical conduction characteristics of the nanoelectronic devices, the array of nanoelectronic devices being logically organized into a plurality of individually operable subsets of the nanoelectronic devices, each subset being operable for only a limited period before operational degradation due to interaction between the bodily fluid and operating nanoelectronic sensors of the subset; in response to control inputs, enabling electrical sensing operation of a selected one of the subsets of the nanoelectronic devices to generate respective sensing output signals while simultaneously disabling such electrical sensing operation of remaining ones of the subsets of the nanoelectronic devices; and generating the control inputs to serially enable electrical operation of successive ones of the subsets of the nanoelectronic devices over an extended period generally equal to the product of the limited period and the number of the subsets of the nanoelectronic devices. - View Dependent Claims (17, 18, 19, 20)
-
Specification