DELIVERY OF A THERAPEUTIC FLUID

• US 20150314063A1
• Filed: 12/06/2013
• Published: 11/05/2015
• Est. Priority Date: 12/07/2012
• Status: Abandoned Application

• Current Assignee: InsuLine Medical Ltd.
• Original Assignee: InsuLine Medical Ltd.
• Inventors: NAGAR, Ron, BITTON, Gabriel
• Application Number:
  US14/650,554
• Publication Number:
  US 20150314063A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2202/0007 introduced into the body
• CPC Class Codes: A61M 2205/05 combined with other kinds of therapy
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 2205/3653 by Joule effect, i.e. electric resistance
• CPC Class Codes: A61M 2205/3693 by mechanical waves, e.g. ultrasonic
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Systems, methods and devices for delivering a therapeutic fluid into tissue are disclosed. The system includes an infusion set having a catheter for delivery of a dose of therapeutic fluid into a tissue via an infusion tube, a treatment element that applies treatment to the tissue proximate to the catheter, a catheter adaptor having a first transponder, a pump adaptor, in communication with the catheter adaptor, having a second transponder that communicates with the first transponder, and an infusion detection sensor that detects an infusion of the therapeutic fluid. Upon detection of an infusion of the therapeutic fluid by the infusion detection sensor, the second transponder communicates a signal indicative of the detected infusion to the first transponder causing the catheter adaptor to apply treatment using the treatment element. At least one of a strength and a duration of the treatment corresponds to a dose of the infused therapeutic fluid.

Claims

1. A system for delivering a therapeutic fluid into a tissue comprising:

an infusion set comprising a catheter for delivery of a dose of the therapeutic fluid into the tissue via an infusion tube;

a treatment element configured to apply a treatment to the tissue proximate to the catheter;

a catheter adaptor comprising a first transponder; and

a pump adaptor in communication with the catheter adaptor and comprising;

a second transponder configured to communicate with the first transponder, and

an infusion detection sensor configured to detect an infusion of the therapeutic fluid;

wherein, upon detection of an infusion of the therapeutic fluid by the infusion detection sensor, the second transponder is configured to communicate a signal indicative of the detected infusion to the first transponder, wherein the catheter adaptor is configured to cause the treatment element to apply treatment to the tissue proximate to the catheter based on at least one of the following;

the signal indicative of the detected infusion and a manual activation of the catheter adaptor causing the treatment element to apply treatment, wherein at least one of a strength and a duration of the treatment is determined based on a dose of the infused therapeutic fluid.

2. The system according to claim 1, wherein the treatment element applies treatment during at least one of the following times:

before infusion of the therapeutic fluid, during infusion of the therapeutic fluid, and after infusion of the therapeutic fluid.

3. The system according to claim 1, wherein at least one of the first transponder and the second transponder includes at least one of the following:

a wireless transponder, and a radio frequency identification device (RFID), an antenna, a transducer, and/or an RLC circuit, an electrical circuit for analog or digital short range communication, or a digital communication mode including WIFI or Bluetooth.

4. The system according to claim 1, wherein the pump adaptor is connected to a pump and a reservoir containing the therapeutic fluid, wherein the pump is configured to pump the therapeutic fluid from the reservoir to the catheter via the infusion tube.

5. The system according to claim 4, wherein the infusion detection sensor is configured to detect an amount of the therapeutic fluid being pumped by the pump based on at least one movement of the pump.

8. The system according to claim 1, wherein the dose of the therapeutic fluid being infused is at or above a predetermined dose.

9. The system according to claim 1, wherein the therapeutic fluid includes at least one of the following:

subcutaneously delivered therapeutic fluids, insulin, rapid-acting insulin, insulin mimetics, insulin analogs, and/or any other types of insulin, pain relief drugs or cancer treatment drugs.

11. The system according to claim 1, wherein:

the pump adaptor includes;

a pump adaptor power source;

a pump adaptor controller; and

wherein the controller, upon receiving an indication from the infusion detection sensor, instructs the second transponder to communicate with the first transponder; and

the catheter adaptor includes;

a catheter adaptor power source;

a catheter adaptor controller; and

at least one first electrical contact configured to be coupled with at least one second electrical contact disposed on the infusion set;

wherein the catheter adaptor controller is configured to process the communication received from the second transponder and generate an instruction to the treatment element to initiate the application of treatment, the generated instruction being provided to the treatment element using the at least one first electrical contact and the at least one second electrical contact.

12. The system according to claim 1, wherein the application of treatment includes at least one of the following:

heating, cooling, mechanical vibrations, suction, massaging, acoustic stimulation, electromagnetic radiation, magnetic stimulation, radio frequency irradiation, microwave irradiation, electrical stimulation, Transcutaneous Electrical Nerve Stimulation (TENS), an additional substance, drugs, medicament, chemicals, biologically active bacteria, biologically inactive bacteria or a combination thereof.

14. The system according to claim 1, wherein the application of treatment is configured to modify a pharmacokinetic and/or a pharmacodynamic profile of the therapeutic fluid being infused.

15. A method for delivering a therapeutic fluid comprising:

providing a system according to claim 1;

initiating infusion of the therapeutic fluid using an infusion pump;

detecting the initiation of the infusion of the therapeutic fluid using the infusion detection sensor;

generating a communication to the first transponder using the second transponder, wherein the communication comprises a signal indicative of the detected infusion; and

activating the treatment element using the catheter adaptor to apply treatment in accordance with a dose of the therapeutic fluid being infused.

16. The method according to claim 15, wherein treatment is applied during at least one of the following times:

before infusion of the therapeutic fluid, during infusion of the therapeutic fluid, and after infusion of the therapeutic fluid.

17. The method according to claim 15, wherein at least one of the first transponder and the second transponder includes at least one of the following:

a wireless transponder, and a radio frequency identification device (RFID), an antenna, a transducer, and/or an RLC circuit, an electrical circuit for analog or digital short range communication, or a digital communication mode including WIFI or Bluetooth.

18. The method according to claim 15,

wherein the pump adaptor is connected to a pump and a reservoir containing the therapeutic fluid, and

wherein the initiating comprises pumping the therapeutic fluid from the reservoir to the catheter via the infusion tube.

19. The method according to claim 18, wherein the detecting includes detecting an amount of the therapeutic fluid being pumped by the pump based on at least one movement of the pump.

22. The method according to claim 15, wherein the dose of the therapeutic fluid being infused is at or above a predetermined dose.

23. The method according to claim 15, wherein the therapeutic fluid includes at least one of the following:

subcutaneously delivered therapeutic fluids, insulin, rapid-acting insulin, insulin mimetics, insulin analogs, and/or any other types of insulin, pain relief drugs or cancer treatment drugs.

25. The method according to claim 15, wherein

the pump adaptor includes:

a pump adaptor power source;

a pump adaptor controller; and

wherein the generating further comprises receiving, using the pump adaptor controller, an indication from the infusion detection sensor and instructing, using the pump adaptor controller, the second transponder to communicate with the first transponder; and

the catheter adaptor includes

a catheter adaptor power source;

a catheter adaptor controller; and

at least one first electrical contact configured to couple with at least one second electrical contact disposed on the infusion set;

wherein the catheter adaptor controller is configured to process the communication received from the second transponder and generate an instruction to the treatment element to apply treatment, the generated instruction being provided to the treatment element using the at least one first electrical contact and the at least one second electrical contact.

26. The method according to claim 15, wherein the application of treatment includes at least one of the following:

heating, cooling, mechanical vibrations, suction, massaging, acoustic stimulation, electromagnetic radiation, magnetic stimulation, radio frequency irradiation, microwave irradiation, electrical stimulation, Transcutaneous Electrical Nerve Stimulation (TENS), an additional substance, drugs, medicament, chemicals, biologically active bacteria, biologically inactive bacteria or a combination thereof.

28. The method according to claim 15, wherein the application of treatment is configured to modify a pharmacokinetic and/or a pharmacodynamic profile of the therapeutic fluid being infused.

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