CARTRIDGE AND APPARATUS FOR PREPARING A BIOLOGICAL SAMPLE
First Claim
1. A cartridge for processing a biological sample, comprising a cartridge-body with:
- a) a reaction chamber with an opening that can be closed by a substrate carrying a sample;
b) a fluidic inlet system for providing at least one reagent fluid to the reaction chamber;
c) a fluidic outlet system for receiving fluid from the reaction chamber;
wherein the fluidic inlet system, the reaction chamber with a substrate closing its opening, and the fluidic outlet system are closed with respect to the exchange of liquids with the environment.
1 Assignment
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Accused Products
Abstract
The invention relates to a cartridge (100) and an associated apparatus (150) for preparing a biological sample, particularly for staining a tissue or cell sample (1). The cartridge (100) comprises a reaction chamber (116) that can be closed by a substrate (140) carrying the sample (1), wherein the reaction chamber (116) is further connected to a fluidic inlet system (113,115) and a fluidic outlet system (123,125). When the substrate (140) closes the reaction chamber, the fluidic inlet system, the reaction chamber, and the fluidic outlet system constitute a fluidic system that is closed to the environment with respect to the exchange of liquids. A pressure-driven flow through the reaction chamber (116) may for example be induced by the actuation of deformable membranes (114,124).
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Citations
15 Claims
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1. A cartridge for processing a biological sample, comprising a cartridge-body with:
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a) a reaction chamber with an opening that can be closed by a substrate carrying a sample; b) a fluidic inlet system for providing at least one reagent fluid to the reaction chamber; c) a fluidic outlet system for receiving fluid from the reaction chamber; wherein the fluidic inlet system, the reaction chamber with a substrate closing its opening, and the fluidic outlet system are closed with respect to the exchange of liquids with the environment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. (canceled)
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12. (canceled)
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13. (canceled)
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14. (canceled)
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15. (canceled)
Specification