Magnetic Resonance Fingerprinting (MRF) With Simultaneous Multivolume Acquisition
First Claim
1. A method for creating a parameter map or an image from data acquired by controlling a magnetic resonance imaging (MRI) apparatus to perform magnetic resonance fingerprinting with simultaneous multivolume acquisition (MRF-SMVA), comprising:
- controlling the MRI apparatus to create a first nuclear magnetic resonance (NMR) excitation in a first volume in a sample according to a first set of magnetic resonance fingerprinting (MRF) parameters;
controlling the MRI apparatus to create a second, different NMR excitation in a second volume in the sample according to a second set of MRF parameters;
controlling the MRI apparatus to acquire first NMR signals produced by the first volume in response to the first NMR excitation;
producing a first signal evolution from the first NMR signals, the first signal evolution having complex values with an arbitrary phase relationship;
controlling the MRI apparatus to acquire second NMR signals produced by the second volume in response to the second NMR excitation;
producing a second signal evolution from the second NMR signals, the second signal evolution having complex values with an arbitrary phase relationship;
simultaneously determining two or more first quantitative magnetic resonance (MR) parameters for a portion of the first volume based on a comparison of the first signal evolution to one or more known signal evolutions;
simultaneously determining two or more second quantitative MR parameters for a portion of the second volume based on a comparison of the second signal evolution to one or more known signal evolutions; and
producing the parameter map or the image based, at least in part, on the two or more first quantitative MR parameters or based, at least in part, on the two or more second quantitative parameters,where the first NMR excitation and the second NMR excitation are active simultaneously, andwhere the first NMR signals and the second NMR signals are acquired simultaneously.
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Abstract
Magnetic resonance fingerprinting (MRF) with simultaneous multivolume acquisition (SMVA) is described. One example nuclear magnetic resonance (NMR) apparatus includes an NMR logic that repetitively and variably samples (k, t, E) spaces associated with different volumes (e.g., slices) in an object to simultaneously acquire sets of NMR signals that are associated with different points in the (k, t, E) spaces. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and compares the NMR signal evolution to reference signal evolutions. Since different volumes are excited differently, resulting signal evolutions can be acquired simultaneously from the different volumes and NMR parameters may be simultaneously determined for the multiple volumes, which reduces acquisition time and parameter map creation time.
52 Citations
48 Claims
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1. A method for creating a parameter map or an image from data acquired by controlling a magnetic resonance imaging (MRI) apparatus to perform magnetic resonance fingerprinting with simultaneous multivolume acquisition (MRF-SMVA), comprising:
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controlling the MRI apparatus to create a first nuclear magnetic resonance (NMR) excitation in a first volume in a sample according to a first set of magnetic resonance fingerprinting (MRF) parameters; controlling the MRI apparatus to create a second, different NMR excitation in a second volume in the sample according to a second set of MRF parameters; controlling the MRI apparatus to acquire first NMR signals produced by the first volume in response to the first NMR excitation; producing a first signal evolution from the first NMR signals, the first signal evolution having complex values with an arbitrary phase relationship; controlling the MRI apparatus to acquire second NMR signals produced by the second volume in response to the second NMR excitation; producing a second signal evolution from the second NMR signals, the second signal evolution having complex values with an arbitrary phase relationship; simultaneously determining two or more first quantitative magnetic resonance (MR) parameters for a portion of the first volume based on a comparison of the first signal evolution to one or more known signal evolutions; simultaneously determining two or more second quantitative MR parameters for a portion of the second volume based on a comparison of the second signal evolution to one or more known signal evolutions; and producing the parameter map or the image based, at least in part, on the two or more first quantitative MR parameters or based, at least in part, on the two or more second quantitative parameters, where the first NMR excitation and the second NMR excitation are active simultaneously, and where the first NMR signals and the second NMR signals are acquired simultaneously. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A method for creating a parameter map or an image from data acquired by controlling a magnetic resonance imaging (MRI) apparatus to perform magnetic resonance fingerprinting with simultaneous multivolume acquisition (MRF-SMVA), comprising:
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controlling the MRI apparatus to create different nuclear magnetic resonance (NMR) excitations in a plurality of volumes in a sample using a plurality of different magnetic resonance fingerprinting (MRF) pulse sequences described by a plurality of MRF parameters; controlling the MRI apparatus to acquire NMR signals produced by members of the plurality of volumes in response to the different NMR excitations; producing a plurality of signal evolutions from the NMR signals; simultaneously determining two or more quantitative magnetic resonance (MR) parameters for a volume in the plurality of volumes based on a comparison of members of the plurality of signal evolutions to one or more known signal evolutions; and producing the parameter map or the image based, at least in part, on the two or more quantitative MR parameters, where at least two members of the plurality of volumes have NMR excitations active simultaneously, and where the NMR signals are acquired simultaneously from the at least two members of the plurality of volumes. - View Dependent Claims (36, 37, 38)
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39. An apparatus, comprising:
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an excitation logic that causes a magnetic resonance fingerprinting (MRF) apparatus to create different MRF excitations in a plurality of different slices in an object, where the different MRF excitations are active at the same time; a nuclear magnetic resonance (NMR) logic that receives a first set of data from the MRF apparatus in response to the MRF apparatus repetitively and variably sampling a (k, t, E) space associated with the object, where the MRF apparatus applies radio frequency (RF) energy and gradients to the object according to an MRF pulse sequence to cause the object to produce the first set of NMR signals, where members of the first set of data are associated with different points in the (k, t, E) space, where t is time and E includes at least T1 and T2, T1 being spin-lattice relaxation and T2 being spin-spin relaxation, and where one or more of, t and E, vary non-linearly, and where the first set of data includes signals from the plurality of slices, a signal logic that produces one or more NMR signal evolutions from the first set of data; a matching logic that selects, from a collection of stored signal evolutions, one or more selected stored signal evolutions that match one or more members of the one or more NMR signal evolutions to within a desired tolerance, and a parameter map logic that simultaneously produces parameter maps or images for members of the plurality of slices based, at least in part, on the one or more selected stored signal evolutions. - View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47)
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48. An apparatus, comprising:
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a collection logic that collects a received signal evolution from multiple simultaneously excited slices of tissue experiencing nuclear magnetic resonance (NMR) in response to a magnetic resonance fingerprinting (MRF) excitation applied to the tissue by a magnetic resonance imaging (MRI) apparatus, where members of the multiple simultaneously excited slices of tissue are experiencing different NMR; a data store that stores a dictionary of MRF signal evolutions, where members of the dictionary are combinations of information associated with two or more resonant species, and where information concerning the composition of the tissue with respect to the two or more resonant species is retrievable using a matched signal evolution; a selection logic that selects a matching member of the dictionary that is most closely related to the received signal evolution and establishes the matching member as the matched signal evolution, and a characterization logic that identifies a category for the tissue based, at least in part, on the composition of the tissue as identified using the matched signal evolution.
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Specification