SUBJECT INFORMATION OBTAINING APPARATUS, METHOD FOR CONTROLLING SUBJECT INFORMATION OBTAINING APPARATUS, AND PROGRAM

• US 20150351639A1
• Filed: 12/03/2013
• Published: 12/10/2015
• Est. Priority Date: 12/28/2012
• Status: Active Application

• Current Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Original Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Inventors: Abe, Hiroshi
• Application Number:
  US14/655,965
• Publication Number:
  US 20150351639A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0035 adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: A61B 8/4416 related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
• CPC Class Codes: A61B 8/5223 for extracting a diagnostic or physiological parameter from medical diagnostic data for algorithms to analyse biomedical images G06T7/0012
• CPC Class Codes: A61B 8/5238 for combining image data of patient, e.g. merging several images from different acquisition modes into one image for image registration algorithms G06T7/30
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

A subject information obtaining apparatus includes a light source that emits light, a photoacoustic wave reception unit that receives a photoacoustic wave generated when the light is radiated onto a subject and that outputs a photoacoustic signal, an acoustic wave transmission unit that transmits an acoustic wave to the subject, an echo reception unit that receives an echo of the acoustic wave and that outputs an echo signal, and a signal processing unit that obtains pieces of optical characteristic information regarding the subject on the basis of the photoacoustic signal and pieces of morphological information regarding the subject on the basis of the echo signal. The signal processing unit obtains similarity between the pieces of morphological information, and, if the similarity is equal to or higher than a certain value, combines the pieces of optical characteristic information corresponding to the pieces of morphological information.

Claims

1. A subject information obtaining apparatus comprising:

a light source configured to emit light;

a photoacoustic wave reception unit configured to receive a photoacoustic wave generated when the light is radiated onto a subject and output a photoacoustic signal;

an acoustic wave transmission unit configured to transmit an acoustic wave to the subject;

an echo reception unit configured to receive an echo of the acoustic wave and output an echo signal; and

a signal processing unit configured to obtain a plurality of pieces of optical characteristic information regarding the subject on the basis of the photoacoustic signal and a plurality of pieces of morphological information regarding the subject on the basis of the echo signal,

wherein the signal processing unit obtains similarity between the plurality of pieces of morphological information, and

wherein, if the similarity is equal to or higher than a certain value, the signal processing unit combines the plurality of pieces of optical characteristic information corresponding to the plurality of pieces of morphological information.

2. The subject information obtaining apparatus according to claim 1, wherein, if the similarity is lower than the certain value, the signal processing unit does not combine the plurality of pieces of optical characteristic information corresponding to the plurality of pieces of morphological information.

3. The subject information obtaining apparatus according to claim 1, wherein the signal processing unit obtains correlation coefficients of the plurality of pieces of morphological information, and obtains the similarity on the basis of the correlation coefficients.

4. The subject information obtaining apparatus according to claim 3, wherein the signal processing unit obtains the correlation coefficients using one of the following methods:

a sum of absolute differences, a sum of squared differences, cross-correlation, normalized cross-correlation, and zero-mean normalized cross-correlation.

5. The subject information obtaining apparatus according to claim 1,

wherein, if the similarity is equal to or higher than the certain value, the signal processing unit obtains differences between positions of the plurality of pieces of morphological information, and

wherein the signal processing unit corrects coordinates of the plurality of pieces of optical characteristic information corresponding to the plurality of pieces of morphological information on the basis of the differences between the positions of the plurality of pieces of morphological information.

6. The subject information obtaining apparatus according to claim 5, wherein the signal processing unit obtains correlation coefficients of the plurality of pieces of morphological information and obtains the differences on the basis of the correlation coefficients.

7. The subject information obtaining apparatus according to claim 1, wherein the signal processing unit combines the plurality of pieces of optical characteristic information by performing one of the following methods:

an arithmetic mean method, a geometric mean method, and a harmonic mean method.

8. The subject information obtaining apparatus according to claim 1, wherein the light source emits light beams having a plurality of wavelengths, wherein the signal processing unit obtains the plurality of pieces of optical characteristic information on the basis of the light beams having the plurality of wavelengths, and wherein the signal processing unit obtains concentration of a substance in the subject by combining the plurality of pieces of optical characteristic information.

9. The subject information obtaining apparatus according to claim 1, wherein the acoustic wave transmission unit and the echo reception unit include the same transducer.

10. The subject information obtaining apparatus according to claim 1, wherein the photoacoustic wave reception unit, the acoustic wave transmission unit, and the echo reception unit include the same transducer.

11. A method for controlling a subject information obtaining apparatus, the method comprising the steps of:

obtaining a photoacoustic signal by receiving a photoacoustic wave generated when light is radiated onto a subject;

transmitting an acoustic wave to the subject;

obtaining an echo signal by receiving an echo of the acoustic wave;

obtaining a plurality of pieces of optical characteristic information regarding the subject on the basis of the photoacoustic signal;

obtaining a plurality of pieces of morphological information regarding the subject on the basis of the echo signal,

obtaining similarity between the plurality of pieces of morphological information; and

combining, if the similarity is equal to or higher than a certain value, the plurality of pieces of optical characteristic information corresponding to the plurality of pieces of morphological information.

12. A non-transitory computer-readable storage medium which records a program for causing a computer to execute the method for controlling a subject information obtaining apparatus according to claim 11.

13. A subject information obtaining apparatus comprising:

a light source configured to emit light;

a photoacoustic wave reception unit configured to receive a photoacoustic wave generated when the light is radiated onto a subject and output a photoacoustic signal; and

a signal processing unit configured to obtain a plurality of pieces of optical characteristic information regarding the subject on the basis of the photoacoustic signal,

wherein the signal processing unit obtains similarity between the plurality of pieces of optical characteristic information, and

wherein, if the similarity is equal to or higher than a certain value, the signal processing unit combines the plurality of pieces of optical characteristic information.

14. A subject information obtaining apparatus comprising:

a light source configured to emit light;

a photoacoustic wave reception unit configured to receive a photoacoustic wave generated when the light is radiated onto a subject and output a photoacoustic signal;

an acoustic wave transmission unit configured to transmit an acoustic wave to the subject;

an echo reception unit configured to receive an echo of the acoustic wave and output an echo signal; and

a signal processing unit configured to obtain a plurality of pieces of optical characteristic information regarding the subject on the basis of the photoacoustic signal and a plurality of pieces of morphological information regarding the subject on the basis of the echo signal,

wherein the signal processing unit obtains first optical characteristic information regarding the subject on the basis of a first photoacoustic signal output from the photoacoustic wave reception unit that has received a photoacoustic wave in a first period,

wherein the signal processing unit obtains first morphological information regarding the subject on the basis of a first echo signal output from the echo reception unit that has received an echo of an acoustic wave in the first period, wherein the signal processing unit obtains second optical characteristic information regarding the subject on the basis of a second photoacoustic signal output from the photoacoustic wave reception unit that has received a photoacoustic wave in a second period, which is different from the first period, wherein the signal processing unit obtains second morphological information regarding the subject on the basis of a second echo signal output from the echo reception unit that has received an echo of an acoustic wave in the second period,

wherein the signal processing unit obtains similarity between the first morphological information and the second morphological information, and wherein, if the similarity is equal to or higher than a certain value, the signal processing unit combines the first optical characteristic information and the second optical characteristic information.

15. The subject information obtaining apparatus according to claim 14, wherein the light source radiates first light in the first period and second light in the second period, and wherein the acoustic wave transmission unit transmits a first acoustic wave in the first period and a second acoustic wave in the second period.