Method And System For Monitoring Depth Of Anaesthesia And Sensory Functioning

• US 20150351657A1
• Filed: 01/17/2014
• Published: 12/10/2015
• Est. Priority Date: 01/17/2013
• Status: Abandoned Application

• Current Assignee: SensoDetect AB
• Original Assignee: SensoDetect AB
• Inventors: Kllstrand, Johan, Holmberg, Jens
• Application Number:
  US14/761,561
• Publication Number:
  US 20150351657A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/38 Acoustic or auditory stimuli
• CPC Class Codes: A61B 5/4821 Determining level or depth of anaesthesia A61B5/1106 takes precedence
• CPC Class Codes: A61B 5/4824 Touch or pain perception evaluation A61B5/4821 takes precedence
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

Methods and systems for measuring depth of anaesthesia and/or perception of pain comprising using brainstem audiometry are described.

Claims

1. An apparatus for monitoring or monitoring a sensory function of a subject, said apparatus comprising:

a sound stimuli generating unit operative to send a sequence of an identical sound stimulus to said subject to evoke neurons response patterns

a detection unit operative to detect a response signal of evoked neurons'"'"' response patterns related to each sound stimuli in said sequence; and

a control unit operative to perform an analysis of said sensory function based on said response signals of evoked neurons'"'"' response patterns detected when stimuli is applied to a sensory function compared to said response signals of evoked neurons'"'"' response patterns detected before and/or after stimuli was applied to said sensory function.

2. The apparatus according to claim 1, wherein said control unit is operative to detect deviations by comparing detected response of evoked neurons'"'"' response patterns to previous detected evoked neurons'"'"' response patterns from said subject.

3. The apparatus according to claim 1, wherein said control unit is further operative to perform a profile matching to detect characteristic aberration in amplitude compared to reference values of said subject.

4. The apparatus according to claim 1, wherein said sound stimuli is generated using a Fast Fourier Transformation-filter.

5. The apparatus according to claim 1, wherein said sound stimuli have a cut-off frequency of between 1000 Hz to 6000 Hz, such as 3000 Hz, such as 4000 Hz.

6. The apparatus according to claim 1, wherein said sound stimuli has a duration of 0.1 ms to 0.2 ms, such as 0.12 to 0.15 ms, such as 0.136 ms.

7. The apparatus according to claim 1, wherein said sound stimuli have a rise and fall of 0.015 ms to 0.03 ms, such as 0.02 ms to 0.025 ms, such as 0.023 ms.

8. The apparatus according to claim 1, wherein said monitored sensory functioning is transmission of pain pulses.

9. The apparatus according to claim 1, wherein said detection of said response signal of evoked neurons'"'"' response patterns is done 0 to 10 ms, such as 0-8 ms, such as 0 to 5 ms, such as 4 to 8 ms, after said related sound stimulus,

10. An method for monitoring or measuring a sensory function of a subject, said method comprising:

generating a sequence of identical sound stimuli and transmitting said sound stimuli to said subject;

detecting a response signal of evoked neurons'"'"' response patterns related to each sound stimuli of said sequence; and

performing an analysis of said sensory function based on said response signals of evoked neurons'"'"' response patterns detected when stimuli is applied to a sensory function compared to said response signals of evoked neurons'"'"' response patterns detected before and/or after stimuli was applied to said sensory function.

11. The method according to claim 10, wherein said analysis comprising detecting deviations by comparing detected response of evoked neurons'"'"' response patterns to previous detected evoked neurons'"'"' response patterns from said subject.

12. The method according to claim 10, wherein said analysis further comprising performing a profile matching to detect characteristic aberration in amplitude compared to reference values of said subject.

13. The method according to claim 10, wherein said sound stimuli is generated using a Fast Fourier Transformation-filter.

14. The method according to claim 10, wherein said sound stimuli have a cut-off frequency between 1000 Hz to 6000 Hz, such as 3000 Hz, such as 4000 Hz.

15. The method according to claim 10, wherein said sound stimuli has a duration of 0.1 ms to 0.2 ms, such as 0.12 to 0.15 ms, such as 0.136 ms.

16. The method according to claim 10, wherein said sound stimuli have a rise and fall of 0.015 ms to 0.03 ms, such as 0.02 ms to 0.025 ms, such as 0.023 ms.

17. The method according to claim 10, wherein said detection of said response signal of evoked neurons'"'"' response patterns is done 0 to 10 ms, such as 0-8 ms, such as 0 to 5 ms, such as 4 to 8 ms, after said related sound stimulus.

18. A computer-readable medium having embodied thereon a computer program for processing by a computer, the computer program comprising a plurality of code segments for carrying out of a method according to claim 10.

19. An apparatus for monitoring depth of anaesthesia of a subject, said apparatus comprising:

a sound stimuli generating unit operative to send a sequence of an identical sound stimulus to said subject to evoke neurons response patterns

a detection unit operative to detect a response signal of evoked neurons'"'"' response patterns related to each sound stimuli in said sequence; and

a control unit operative to perform an analysis of said response signal of evoked neurons'"'"' response patterns.

26. The apparatus according to claim 19, wherein said monitored sensory functioning is transmission of pain pulses.

20-25. -25. (canceled)

27-39. -39. (canceled)