INGESTIBLE DEVICE WITH PHARMACEUTICAL PRODUCT

• US 20150352343A1
• Filed: 08/18/2015
• Published: 12/10/2015
• Est. Priority Date: 11/22/2010
• Status: Abandoned Application

• Current Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Original Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Inventors: Hafezi, Hooman, Schmidt, Raymond
• Application Number:
  US14/829,229
• Publication Number:
  US 20150352343A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61J 3/071 into the form of telescopically engaged two-piece capsules
• CPC Class Codes: A61K 9/0097 Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips intradermal microneedle arrays A61K9/0021; MEMS in general B81B7/02
• CPC Class Codes: A61K 9/4808 characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release capsules filled with granules or microparticles A61K9/16; filled with microcapsules or coated microparticles A61K9/50; with mixture of different granules, microcapsules, (coated) microparticles A61K9/5084
• CPC Class Codes: A61M 2205/0238 the material being a coating or protective layer
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/82 Internal energy supply devices
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

A device for placement within a capsule. The device includes a unit to encode information in a current signature, the unit including a partial power source. The device further including a flexible membrane secured to the unit. The membrane engages the wall of the capsule and holds the device in place within the capsule.

Claims

1. A device for placement within a capsule, the device comprising:

an assembly including;

a unit to encode information in a current signature, the unit comprising a partial power source; and

a flexible membrane secured to the unit, wherein the membrane engages the capsule'"'"'s wall and holds the device in place within the capsule.

2. The device of claim 1, further comprising a protective coating surrounding the assembly.

3. The device of claim 1, further comprising a first protective sheet secured to an upper surface of the assembly and a second protective sheet secured to a lower surface of the assembly.

4. The device of claim 3, wherein the first protective sheet and the second protective sheet are secured to each other through a plurality of holes defined by the flexible membrane.

5. The device of claim 3, wherein the first protective sheet and the second protective sheet are secured to each other at the edge of the assembly and extend beyond the perimeter of the assembly such that the assembly is enclosed within the protective sheets.

6. The device of claim 1, wherein the unit includes:

a first material secured to a support structure; and

a second material secured to the support structure and electrically isolated from the first material, such that the first material and second material represent a chemical voltage potential when in contact with a conducting fluid.

7. The device of claim 6, wherein the support structure comprises a control module electrically connected to the first material and the second material to control the conductance between the first material and the second material, wherein the control module encodes the information in the current signature by altering the conductance.

8. The device of claim 1, wherein the flexible membrane includes a plurality of legs that engage the capsule'"'"'s wall when the assembly is pressed into the capsule.

9. The device of claim 1, wherein the flexible membrane includes a plurality of extensions shaped to fit within the capsule and hold the assembly in place.