BARORECEPTOR MAPPING SYSTEM

• US 20150366467A1
• Filed: 06/18/2015
• Published: 12/24/2015
• Est. Priority Date: 06/19/2014
• Status: Abandoned Application

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: De Kock, Andrew L., Mokelke, Eric A., Soltis, Brian, Blood, James E., Gordon, Jack, Giwoyna, Doug E.
• Application Number:
  US14/743,985
• Publication Number:
  US 20150366467A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 5/02028 Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0531 Measuring skin impedance
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61N 1/0476 Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/36117 for treating hypertension
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: Y10T 156/1028 by bending, drawing or stretch forming sheet to assume shape of configured lamina while in contact therewith

Abstract

A system including a mapping device, a stimulator, and a marker. The mapping device includes a plurality of electrodes to be situated on a baroreceptor region of a patient to map baroreceptors in the baroreceptor region. The stimulator is to stimulate selected electrodes of the plurality of electrodes to obtain physiological responses from the patient in response to stimulation of the selected electrodes. The marker is to be attached to the patient to mark a location of at least one of the selected electrodes based on an analysis of the physiological responses from the patient, where the marker is to maintain its location on the patient as the mapping device is removed from the patient.

Claims

1. A system, comprising:

a mapping device that includes a plurality of electrodes to be situated on a baroreceptor region of a patient;

a stimulator to stimulate selected electrodes of the plurality of electrodes to obtain physiological responses from the patient in response to stimulation of the selected electrodes; and

a marker to be attached to the patient and to mark a location of at least one of the selected electrodes based on an analysis of the physiological responses from the patient.

2. The system of claim 1, comprising an implantable device that includes at least one implantable electrode to be aligned on the baroreceptor region via the marker and sutured into place on the baroreceptor region.

3. The system of claim 2, wherein the mapping device includes at least one marking aperture that extends through the mapping device and the implantable device includes at least one aligning aperture that extends through the implantable device, and the marker is to be attached to the patient through the at least one marking aperture and the implantable device is to be aligned on the baroreceptor region via the at least one aligning aperture and the marker.

4. The system of claim 1, wherein the mapping device includes at least one aperture that extends through the mapping device and the marker is to be attached to the patient through the at least one aperture.

5. The system of claim 1, wherein the mapping device includes at least one aperture that extends through the mapping device and is adjacent at least one of the electrodes of the plurality of electrodes.

6. The system of claim 1, wherein at least one of the electrodes has a closed curve electrode shape and the mapping device includes at least one aperture that extends through the mapping device and through an interior region of the closed curve electrode shape.

7. The system of claim 1, wherein the marker includes at least one of a pin shape, a thread, a hook, and a stop to regulate insertion distance of the marker in the patient and the marker is to be attached to the patient through a through-hole aperture in the mapping device.

8. The system of claim 1, wherein the mapping device includes a self-curling sheet that fixes the mapping device to the patient.

9. The system of claim 1, comprising a sensor to sense the physiological responses and provide signals that indicate the physiological responses from the patient, wherein the stimulator receives the signals and analyzes the signals to determine the location of the at least one of the selected electrodes to be marked by the marker.

10. A method comprising:

maintaining a mapping device that includes a plurality of electrodes on a baroreceptor region of a patient;

stimulating selected electrodes of the plurality of electrodes with a stimulator to obtain physiological responses from the patient in response to stimulation of the selected electrodes;

marking a location of at least one of the selected electrodes on the baroreceptor region of the patient with a marker based on an analysis of the physiological responses from the patient;

removing the mapping device from the patient; and

maintaining the marker at the location of the at least one of the selected electrodes on the baroreceptor region of the patient.

11. The method of claim 10, wherein marking a location includes attaching the marker to the patient through at least one marking aperture that extends through the mapping device.

12. The method of claim 10, wherein marking a location includes at least one of sticking a pin into the patient through at least one marking aperture that extends through the mapping device and suturing a thread into the patient through the at least one marking aperture that extends through the mapping device.

13. The method of claim 10, comprising:

aligning an implantable device with the marker on the baroreceptor region; and

securing, to the patient, the implantable device aligned with the marker on the baroreceptor region.

14. The method of claim 10, comprising aligning an implantable device on the baroreceptor region by positioning the marker through at least one aligning aperture that extends through the implantable device.

15. The method of claim 10, wherein the marker is one of a pin and a sutured thread and comprising aligning an implantable device on the baroreceptor region by positioning the marker through at least one aligning aperture that extends through the implantable device.

16. The method of claim 10, wherein maintaining a mapping device includes wrapping a self-curling mapping device around at least one body part of the patient.

17. The method of claim 10, comprising:

sensing the physiological responses from the patient with a sensor;

providing signals that indicate the physiological responses from the patient;

receiving the signals at the stimulator; and

analyzing the signals with the stimulator to determine the location of the at least one of the selected electrodes on the baroreceptor region of the patient to be marked by the marker.

18. A method of making a self-curling mapping device, the method including:

unrolling and tacking a self-curling sheet to a flat surface;

applying a layer of adhesive to at least part of the inward curling portion of the self-curling sheet;

laminating the mapping device onto the self-curling sheet via the adhesive to provide a laminated assembly;

curling the laminated assembly around a mandrel to allow the adhesive to cure in a curled state; and

uncurling the self-curling mapping device.

19. The method of claim 18, wherein the self-curling sheet includes a self-curling silicone sheet.

20. The method of claim 18, wherein the layer of adhesive includes a layer of silicone adhesive.