MASSIVELY PARALLEL SINGLE CELL ANALYSIS
First Claim
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1. A composition comprising:
- a substrate comprising at least 1,000 wells wherein a plurality of wells comprise a single cell from a population of cells and a single bead from a population of beads.
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Abstract
The disclosure provides for methods, compositions, and kits for multiplex nucleic acid analysis of single cells. The methods, compositions and systems may be used for massively parallel single cell sequencing. The methods, compositions and systems may be used to analyze thousands of cells concurrently. The thousands of cells may comprise a mixed population of cells (e.g., cells of different types or subtypes, different sizes).
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30 Claims
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1. A composition comprising:
- a substrate comprising at least 1,000 wells wherein a plurality of wells comprise a single cell from a population of cells and a single bead from a population of beads.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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28. A composition comprising:
- a substrate comprising at least 1,000 wells wherein a plurality of wells comprise a lysate from a single cell from a population of cells and a single bead from a population of beads.
- View Dependent Claims (29, 30)
Specification