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RANDOM ARRAY DNA ANALYSIS BY HYBRIDIZATION

  • US 20160023180A1
  • Filed: 10/07/2015
  • Published: 01/28/2016
  • Est. Priority Date: 12/20/2002
  • Status: Abandoned Application
First Claim
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1. An apparatus for determining sequence information for a target nucleic acid by probe hybridization, comprising:

  • a sample integration module configured for mixing, introducing, and/or removing reagents;

    a disposable plug-in reaction cartridge configured for contacting an array of target nucleic acid fragments with probe pools, wherein the reaction cartridge comprises a slot for securing an array of single DNA molecules or amplicons, and quick connect ports for flow-through connection to the sample integration module;

    a subsystem configured for illuminating fluorophores on an array in the reaction cartridge; and

    a subsystem configured for detecting fluorophores on an array in the reaction cartridge.

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