Means for Controlled Sealing of Endovascular Devices
First Claim
1. A fluid isolatable expandable seal for a vascular device comprisinga hydrogel strip,a polymeric film encapsulating the hydrogel strip,the encapsulated strip being positioned on the exterior circumference of the vascular device, wherein the exterior of the encapsulated strip expands upon contact with a fluid, andThe film has a slit that opens to allow fluid to hydrate the hydrogel strip.
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Accused Products
Abstract
Expandable sealing means for endoluminal devices have been developed for controlled activation. The devices have the benefits of a low profile mechanism (for both self-expanding and balloon-expanding prostheses), contained, not open, release of the material, active conformation to the “leak sites” such that leakage areas are filled without disrupting the physical and functional integrity of the prosthesis, and on-demand, controlled activation, that may not be pressure activated.
49 Citations
28 Claims
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1. A fluid isolatable expandable seal for a vascular device comprising
a hydrogel strip, a polymeric film encapsulating the hydrogel strip, the encapsulated strip being positioned on the exterior circumference of the vascular device, wherein the exterior of the encapsulated strip expands upon contact with a fluid, and The film has a slit that opens to allow fluid to hydrate the hydrogel strip.
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4. A fluid isolatable expandable seal for a vascular device comprising
a polymeric film expanding to form a seal which is positioned on the exterior circumference of the vascular device, wherein the exterior of the encapsulated strip expands upon contact with a fluid, and the film has an opening that is open to allow fluid to fill the expandable film, which self-seals by positive displacement when the expandable film is fully hydrated.
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7. A fluid isolatable expandable seal for a vascular device comprising
a polymeric film blow molded to form a “ - D”
balloon over a porous mesh, which is heat or laser welded to seal a hydrogel strip between the film and the mesh. - View Dependent Claims (8, 9, 10)
- D”
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11. A stent-balloon-vascular device with seal comprising
a stent containing a vascular device and balloon for centering of the device as it is positioned, a seal on the inside of the stent containing the vascular device, wherein the seal is positioned in abutment with the device, so that the seal is flipped out and over the end edge of the vascular device as the device is expanded and immediately prior to positioning, wherein the device is centered by the balloon.
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13. A removable casing formed of a metal or polymer for fluidic isolation of an expandable seal on the exterior of a vascular device,
the casing having as in a “ - U”
shape that allows for complete insertion of the seal within the “
U”
cavity when attached to the exterior circumference of the vascular device,wherein the open end of the “
U”
cavity has O-rings and a locking mechanism that fit together to compress the O-rings to bring them under pressure, thereby allowing the formation of a fluid-tight seal.
- U”
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14. An endoluminal seal for sealing an expandable endoluminal implant or prosthesis to a wall of a lumen of a subject, the endoluminal seal comprising:
an expandable film containing a foaming material activatable by exposure to a fluid or a foaming agent, secured to the exterior circumference of a vascular device, the vascular device having on the interior circumference spring struts which push through the vascular implant or prosthesis to force the foam within the expandable material outward from the vascular device.
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15. An endoluminal seal for sealing an expandable vascular device, the endoluminal seal comprising:
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a polymeric fluid impermeable membrane removable casing formed of a metal or polymer for fluidic isolation of an expandable seal on the exterior of a vascular device, an expandable material selected from the group consisting of hydrogels, sponges and foams optionally spray dried or chemically coupled to the interior of the endoluminal seal, a first membrane adjacent to and containing the expandable material; wherein the expandable material is activated by exposure to a fluid or a foaming agent, and a fluid impermeable membrane fluidically isolating the expandable material until exposed to an aqueous solution under physiological conditions. - View Dependent Claims (16, 17)
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18. A plug for preventing exposure of an endoluminal seal for sealing an expandable vascular device including tissue which must be stored hydrated,
the endoluminal seal comprising an expandable material selected from the group consisting of hydrogels, sponges and foams optionally spray dried or chemically coupled to the interior of the endoluminal seal, wherein the expandable material is activated by exposure to a fluid or a foaming agent, the compliant plug being shaped to be inserted into the vascular device to prevent fluid from passing beyond the tissue to reach the seal.
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22. A metal film or metal-polymer laminate for preventing exposure of an endoluminal seal for sealing an expandable vascular device including tissue which must be stored hydrated,
the endoluminal seal comprising an expandable material selected from the group consisting of hydrogels, sponges and foams optionally spray dried or chemically coupled to the interior of the endoluminal seal, wherein the expandable material is activated by exposure to a fluid or a foaming agent, the laminate comprising a metallic film or a metallic film with a polymer laminate that acts as a barrier during the storage of the vascular device in fluid and is removable by peeling off the metal film or laminate along a pre-scored tear line.
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24. A packaging case for an endoluminal seal for sealing an expandable vascular device including tissue which must be stored hydrated,
the endoluminal seal comprising an expandable material selected from the group consisting of hydrogels, sponges and foams optionally spray dried or chemically coupled to the interior of the endoluminal seal, wherein the expandable material is activated by exposure to a fluid or a foaming agent, the container having an upper and a lower compartment, which are not in fluid communication.
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28. A fluid absorbant material for placement within a vascular device to keep only the tissue portion hydrated.
Specification