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SYSTEMS AND METHODS TO ASSES MICROBIOMES AND TREATMENTS THEREOF

  • US 20160040216A1
  • Filed: 04/04/2014
  • Published: 02/11/2016
  • Est. Priority Date: 04/05/2013
  • Status: Active Application
First Claim
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1. A method of diagnosing, monitoring the treatment of and/or predicting success or failure of therapy of bacterial vaginosis (BV) in a subject comprising:

  • amplifying total bacterial DNA present in a vaginal sample from the subject; and

    selectively amplifying non-Lactobacillus (LB) species DNA in the sample by amplifying total bacterial DNA while specifically blocking amplification of bacterial DNA from LB species,wherein the relative abundance of non-LB species is indicative of the presence of BV.

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