SYSTEM, METHOD AND APPARATUS WITH MULTIPLE RESERVOIRS FOR IN SITU CALIBRATION OF IMPLANTABLE SENSORS
First Claim
1. A subcutaneous sensor system with multiple reservoirs for calibrating solutions comprising:
- a sensor having a sensor output;
a plurality of reservoirs provided with a corresponding plurality of reservoir outlets;
a plurality of pumps provided with a corresponding plurality of pump inlets and a corresponding plurality of pump outlets, wherein the plurality of pump inlets are coupled to the plurality of reservoir outlets;
a mixer provided with a plurality of mixer inlets and a mixer outlet, wherein the plurality of mixer inlets are coupled to the plurality of pump outlets; and
a controller having an input coupled to the sensor output and a plurality of control outputs coupled to the plurality of pumps and the mixer.
1 Assignment
0 Petitions
Accused Products
Abstract
A subcutaneous sensor system includes a sensor, a plurality of reservoirs, a plurality of pumps, a mixer provided with a plurality of mixer inlets and a mixer outlet, and a controller having an input coupled to the sensor output and a plurality of control outputs coupled to the plurality of pumps and the mixer. In certain embodiments, the system further includes an enclosure for the reservoirs, the pumps, the mixer and the controller, e.g. in the form of a skin patch or in the form of an implantable enclosure. In certain embodiments, the sensor is external to the enclosure and implanted beneath the skin tissue.
-
Citations
20 Claims
-
1. A subcutaneous sensor system with multiple reservoirs for calibrating solutions comprising:
-
a sensor having a sensor output; a plurality of reservoirs provided with a corresponding plurality of reservoir outlets; a plurality of pumps provided with a corresponding plurality of pump inlets and a corresponding plurality of pump outlets, wherein the plurality of pump inlets are coupled to the plurality of reservoir outlets; a mixer provided with a plurality of mixer inlets and a mixer outlet, wherein the plurality of mixer inlets are coupled to the plurality of pump outlets; and a controller having an input coupled to the sensor output and a plurality of control outputs coupled to the plurality of pumps and the mixer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
-
-
20. A method for operating a subcutaneous sensor system with multiple reservoirs for calibrating solutions comprising:
-
detecting the presence of calibration-triggering event with a microcontroller; measuring an initial value from a subcutaneous sensor; bathing the sensor with a first calibration solution having a different value than the initial value, the first calibration solution being provided from at least one of a plurality of reservoirs; measuring a first calibration value from the sensor that is associated with the first calibration solution; bathing the sensor with a second calibration solution having about the same value as the initial value, the second calibration solution being provided by at least one of the plurality of reservoirs; calculating the gain (m) and offset (b) for the sensor, whereby the transfer function f(x) for the sensor comprises y=f(x)=mx+b; and using the transfer function to measure a calibrated sensor value of the sensor.
-
Specification