DEEP BRAIN STIMULATION CURRENT STEERING WITH SPLIT ELECTRODES

• US 20160074651A1
• Filed: 11/20/2015
• Published: 03/17/2016
• Est. Priority Date: 04/16/2009
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Peterson, David Karl Lee, Lane, Courtney, Pianca, Anne Margaret, Moffitt, Michael Adam, Oleksyn, Thomas A., Bradley, Kerry
• Granted Patent: US 9,393,403 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/20 continuous direct currents
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/36182 Direction of the electrical field, e.g. with sleeve around stimulating electrode
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration

Abstract

A device for brain stimulation includes a lead having a longitudinal surface, a proximal end, a distal end and a lead body. The device also includes a plurality of electrodes disposed along the longitudinal surface of the lead near the distal end of the lead. The plurality of electrodes includes a first set of segmented electrodes comprising at least two segmented electrodes disposed around a circumference of the lend at a first longitudinal position along the lead; and a second set of segmented electrodes comprising at least two segmented electrodes disposed around a circumference of the lead at a second longitudinal position along the lead. The device further includes one or more conductors that electrically couple together all of the segmented electrodes of the first set of segmented electrodes.

Claims

1. An implantable stimulation lead, comprising:

a lead body having a longitudinal surface and a distal end;

a plurality of electrodes disposed along the longitudinal surface of the lead body near the distal end of the lead body, the plurality of electrodes comprising;

a plurality of sets of segmented electrodes spaced apart axially along the longitudinal surface of the lead body, each set comprising at least three segmented electrodes disposed around a circumference of the lead body at a longitudinal position along the lead body, and

a tip electrode disposed at, and covering, the distal end of the lead body; and

a plurality of conductors extending along the lead body and coupling to the electrodes.

2. The lead of claim 1, wherein each of the sets of segmented electrodes consists of three segmented electrodes.

3. The lead of claim 1, wherein each of the sets of segmented electrodes have a same number of segmented electrodes.

4. The lead of claim 3, wherein the plurality of sets comprises a first set and a second set disposed at first and second longitudinal positions, respectively, along the lead body.

5. The lead of claim 4, wherein the segmented electrodes of the first set are aligned with the segmented electrodes of the second set along the longitudinal surface of the lead body.

6. The lead of claim 4, wherein the segmented electrodes of the first set are staggered with respect to the segmented electrodes of the second set along the longitudinal surface of the lead body.

7. The lead of claim 4, wherein the plurality of electrodes further comprises a ring electrode disposed at a third longitudinal position along the lead body.

8. The lead of claim 7, wherein the third longitudinal position is proximal to the first and second longitudinal positions along the lead body.

9. The lead of claim 1, wherein the lead is configured and arranged for implantation in a brain of a human.

10. The lead of claim 1, wherein the plurality of sets of segmented electrodes comprises at least three sets of segmented electrodes.

11. The lead of claim 1, wherein the plurality of electrodes further comprises a ring electrode disposed at another longitudinal position along the lead body.

12. The lead of claim 11, wherein the ring electrode is disposed proximal to all of the segmented electrodes.

13. The lead of claim 1, wherein the plurality of electrodes is arranged in a 1-3-3-1 arrangement.

14. The lead of claim 1, wherein the tip electrode has a surface area larger than at least one of the segmented electrodes.

15. An implantable stimulation system, comprising:

the lead of claim 1; and

a control module coupleable to the lead.

16. The implantable stimulation system of claim 15, wherein the control module is a constant-current device.

17. A method for brain stimulation, the method comprising:

inserting the lead of claim 1 into a brain of a human;

coupling the lead to a control module; and

generating electrical signals, using the control module, at one or more of the plurality of electrodes to stimulate at least one target neuron of the brain.

18. A method for brain stimulation, the method comprising:

inserting the lead of claim 1 into a brain of a human;

selectively producing at least one of an anodic current or a cathodic current at the plurality of segmented electrodes to stimulate a target neuron using the plurality of electrodes; and

incrementally shifting the anodic current or the cathodic current in at least two incremental steps from any one of the plurality of segmented electrodes to an adjacent one of the plurality of segmented electrodes.

19. The method of claim 18, wherein incrementally shifting the anodic current or the cathodic current comprises incrementally shifting the anodic current or the cathodic current at increments less than or equal to 25%.

20. The method of claim 18, wherein incrementally shifting the anodic current or the cathodic current comprises incrementally shifting the anodic current from any one of the plurality of segmented electrodes to an adjacent one of the plurality of segmented electrodes at a first increment, and incrementally shifting the cathodic current from any one of the plurality of segmented electrodes to an adjacent one of the plurality of segmented electrodes at a second increment.