TRANSCATHETER PROSTHETIC VALVE FOR MITRAL OR TRICUSPID VALVE REPLACEMENT

• US 20160089235A1
• Filed: 05/22/2013
• Published: 03/31/2016
• Est. Priority Date: 05/22/2013
• Status: Abandoned Application

• Current Assignee: ValCare Medical, Inc.
• Original Assignee: ValCare, Inc.
• Inventors: YELLIN, Nadav
• Application Number:
  US14/891,189
• Publication Number:
  US 20160089235A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/243 Deployment by mechanical expansion
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0025 Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/006 modular
• CPC Class Codes: A61F 2250/0069 Sealing means

Abstract

A prosthesis secures a replacement valve in a heart. The prosthesis includes a radially expandable inflow section and outflow section, and migration blocker rods. The inflow section has a tapered shape and is implanted within an atrium of a heart adjacent a native valve annulus. The outflow section couples to the inflow section, and is configured to be implanted through the native valve annulus and at least partially within a ventricle of the heart. The migration blocker rods extend circumferentially around at least a portion of the outflow section and hold native leaflets of the heart valve. In a contracted configuration, the prosthesis may be implanted through a catheter into the heart. In an expanded configuration, the tapered shape of the inflow section in the atrium cooperates with the migration blockers in the ventricle to hold the prosthesis against the native valve annulus.

Claims

1. A prosthetic mitral valve assembly, comprising:

a radially expandable stent including;

an upper section anatomically configured to fit to a mitral valve annulus within a left atrium of a heart;

a lower section coupled to the upper section and configured to fit within the mitral valve annulus; and

migration blocker rods extending around at least a portion of a circumference of the lower section, the migration blocker rods to prevent axial movement of the stent with respect to the mitral valve annulus; and

a replacement valve coupled to the stent.

2. The prosthetic mitral valve assembly of claim 1, wherein the radially expandable stent is configured to expand into clamping the mitral valve annulus by expanding from both sides of the mitral valve annulus, and wherein the migration blocker rods are behind native leaflets in a left ventricle and the upper section is above the mitral valve annulus in a left atrium.

3. The prosthetic mitral valve assembly of claim 1, wherein the replacement valve comprises a bicuspid or tricuspid valve.

4. The prosthetic mitral valve assembly of claim 1, wherein the migration blocker rods comprise two or more migration blocker rods that are configured to lock together during implantation.

5. The prosthetic mitral valve assembly of claim 1, wherein the migration blocker rods comprise two or more migration blocker rods configured to lock into the upper section through the mitral valve annulus.

6. The prosthetic mitral valve assembly of claim 1, wherein the migration blocker rods comprise two or more migration blocker rods comprising barbs to prevent rocking.

7. A prosthesis for securing a percutaneously implantable replacement valve in a heart, comprising:

a radially expandable inflow section configured, in a deployed configuration, to be implanted within an atrium of a heart adjacent a native valve annulus of a heart valve, the inflow section including a proximal opening and a distal opening, the proximal opening having a greater circumference than that of the distal opening such that the inflow section is tapered;

a radially expandable outflow section coupled to the distal opening of the inflow section, the outflow section configured, in a deployed configuration, to be implanted through the native valve annulus and at least partially within a ventricle of the heart; and

two or more migration blocker rods extending circumferentially around at least a portion of the outflow section, a gap between the two or more migration blockers and the outflow section configured to hold native leaflets of the heart valve;

wherein, in a contracted configuration, the prosthesis is configured to be implanted through a catheter into the heart; and

wherein, in an expanded configuration, the tapered shape of the inflow section in the atrium cooperates with the two or more migration blockers in the ventricle to hold the prosthesis against the native valve annulus.

8. The prosthesis of claim 7, wherein, in the expanded configuration, the proximal opening of the inflow section, the distal opening of the inflow section, and a circumference of the outflow section are each substantially circular.

9. The prosthesis of claim 7, wherein, in the expanded configuration, the proximal opening of the inflow section is elliptical, and the distal opening of the inflow section and a circumference of the outflow section are each substantially circular.

10. The prosthesis of claim 7, wherein, in the expanded configuration, the proximal opening of the inflow section, the distal opening of the inflow section, and a circumference of the outflow section are each elliptical.

11. The prosthesis of claim 7, wherein, in the expanded configuration, the proximal opening of the inflow section is substantially circular, and the distal opening of the inflow section and a circumference of the outflow section are each elliptical.

12. The prosthesis of claim 7, wherein the inflow section comprises a shape memory material, and wherein the outflow section comprises one or more rows of expandable struts.

13. The prosthesis of claim 7, wherein respective ends of the two or more migration blocker rods are configured to lock together during deployment.

14. The prosthesis of claim 7, wherein the two or more migration blocker rods comprise barbs configured to extend, in the expanded configuration, through the native valve annulus and lock into the inflow section.

15. The prosthesis of claim 7, wherein the inflow section and the outflow section are separable from one another, the prosthesis further comprising a plurality of attachment members to removably couple the outflow section to the inflow section.

16. The prosthesis of claim 7, wherein the inflow section is configured to secure a replacement valve.