EXTENDED RELEASE OF NEUREGULIN FOR TREATING HEART FAILURE
First Claim
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1. A method for preventing, treating or delaying a cardiovascular disease or disorder in a mammal, the method comprising subcutaneous extended release of neuregulin into a mammal in an amount of 0.3 μ
- g/kg/day to 3.0 μ
g/kg/day, wherein the subcutaneous extended release of neuregulin into a mammal is accomplished through the use of a pump.
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Abstract
The present invention provides methods and kits for preventing, treating or delaying various cardiovascular diseases or disorders especially heart failure by extended release of neuregulin to a mammal. Moreover, the extended release of neuregulin is administered by subcutaneous infusion with a pump.
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Citations
32 Claims
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1. A method for preventing, treating or delaying a cardiovascular disease or disorder in a mammal, the method comprising subcutaneous extended release of neuregulin into a mammal in an amount of 0.3 μ
- g/kg/day to 3.0 μ
g/kg/day, wherein the subcutaneous extended release of neuregulin into a mammal is accomplished through the use of a pump. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
- g/kg/day to 3.0 μ
- 27. A kit for preventing, treating or delaying a cardiovascular disease or disorder in a mammal, the kit comprising a neuregulin composition or formulation and a pump.
Specification