DETERMINING ARTERIAL PULSE TRANSIT TIME FROM TIME-SERIES SIGNALS OBTAINED AT PROXIMAL AND DISTAL ARTERIAL SITES
First Claim
1. A method for determining arterial pulse wave transit time for a subject, comprising:
- receiving a time-series signal for each of a proximal and distal arterial site of a subject'"'"'s body, said time-series signals being derived from any of;
a contact-based photoplethysmographic (PPG) device and from processing image frames acquired by a video imaging device capable of registering a videoplethysmographic (PPG) signal on a least one imaging channel use to acquire that video;
obtaining a proximal and distal analytic signal each comprising a first component that is a waveform of a respective received time-series signal and a second component that is a transform of that waveform;
determining a phase function with respect to time for said first and second components of each of said proximal and distal analytic signals;
subtracting said phase function for said proximal waveform from said phase function for said distal waveform to obtain a phase difference; and
processing said phase difference with said subject'"'"'s heart rate to determine an arterial pulse wave transit time between said proximal and distal arterial sites.
1 Assignment
0 Petitions
Accused Products
Abstract
What is disclosed is a system and method for determining arterial pulse transit time (PTT) for a subject. In one embodiment, time-series signals are received for each of a proximal and distal arterial site of a subject'"'"'s body which represent blood volume changes in the microvascular tissue at each site. A proximal and distal analytic signal is obtained which has a first component being a waveform of the respective time-series signal and a second component being a transform of the respective waveform. A phase function is determined for the first and second components of each analytic signal. The phase function obtained for the proximal waveform is then subtracted from the phase function obtained for the distal waveform to get a phase difference. The phase difference is analyzed with the subject'"'"'s heart rate to determine an arterial pulse wave transit time between the two proximal and distal sites.
69 Citations
30 Claims
-
1. A method for determining arterial pulse wave transit time for a subject, comprising:
-
receiving a time-series signal for each of a proximal and distal arterial site of a subject'"'"'s body, said time-series signals being derived from any of;
a contact-based photoplethysmographic (PPG) device and from processing image frames acquired by a video imaging device capable of registering a videoplethysmographic (PPG) signal on a least one imaging channel use to acquire that video;obtaining a proximal and distal analytic signal each comprising a first component that is a waveform of a respective received time-series signal and a second component that is a transform of that waveform; determining a phase function with respect to time for said first and second components of each of said proximal and distal analytic signals; subtracting said phase function for said proximal waveform from said phase function for said distal waveform to obtain a phase difference; and processing said phase difference with said subject'"'"'s heart rate to determine an arterial pulse wave transit time between said proximal and distal arterial sites. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. A system for determining arterial pulse wave transit time (PTT) for a subject, the system comprising:
-
a storage device; a processor in communication with a memory and said storage device, said processor executing machine readable instructions for performing; receiving a time-series signal for each of a proximal and distal arterial site of a subject'"'"'s body, said time-series signals being derived from any of;
a contact-based photoplethysmographic (PPG) device and from processing image frames acquired by a video imaging device capable of registering a videoplethysmographic (PPG) signal on a least one imaging channel use to acquire that video;obtaining a proximal and distal analytic signal each comprising a first component that is a waveform of a respective received time-series signal and a second component that is a transform of that waveform; determining a phase function with respect to time for said first and second components of each of said proximal and distal analytic signals; subtracting said phase function for said proximal waveform from said phase function for said distal waveform to obtain a phase difference; and processing said phase difference with said subject'"'"'s heart rate to determine an arterial pulse wave transit time between said proximal and distal arterial sites. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
-
Specification