SENSOR HAVING CHEMICAL INSPECTING FUNCTION AND THE INSPECTING MATERIAL CONTAINED THEREIN

• US 20160109436A1
• Filed: 04/21/2015
• Published: 04/21/2016
• Est. Priority Date: 10/16/2014
• Status: Abandoned Application

• Current Assignee: National Tsing Hua University
• Original Assignee: National Tsing Hua University
• Inventors: YANG, Chung-Yao, CHENG, Chao-Min, LIN, Szu-Ting
• Application Number:
  US14/692,347
• Publication Number:
  US 20160109436A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: G01N 33/525 Multi-layer analytical elements

Abstract

The present invention provides a sensor having chemical inspecting function and the inspecting material contained therein. In simple terms, one of the major features of the present invention is to reduce the detection area contacted with air between the gel and the inspecting material so as to slow down the degradation thereof. The other feature of the invention is to provide the detailed compositional parameters required by the inspecting material in the said process so as to obtain a balanced value between the cost and the visibility. By the present invention, the problem of short retention period of the personal hygiene item is herein solved.

Claims

1. An inspecting material, comprising at least one gel and a reacting substance, the gel for covering the reacting substance to reduce a contact area between air and the reacting substance, wherein an analyte penetrates the gel to react with the reacting substance for changing the color of the reacting substance when the analyte is contacted with the inspecting material.

2. The inspecting material of claim 1, wherein the gel is a water-insoluble polymer material with at least one series of holes penetrated by the analyte for making the analyte to be contacted with the reacting substance.

3. The inspecting material of claim 1, wherein the gel is a water-soluble polymer material compatible with the analyte penetrating the gel by melting the gel to contact with the reacting substance.

4. The inspecting material of claim 1, wherein the reacting substance is a nitrite detection reagent comprised in the inspecting material, the proportion of the nitrite detection reagent comprised in the inspecting material is from 20% to 66%, wherein the efficiency is the best when the proportion is under 29%, and the detectable molar concentration of the analyze of the reacting substance is between 0.1 mM and 5 mM.

5. The inspecting material of claim 1, wherein the reacting substance is a glucose detection reagent comprised in the inspecting material, the proportion of the glucose detection reagent comprised in the inspecting material is from 10% to 50%, wherein the efficiency is the best when the proportion is under 20%, and the detectable molar concentration of the analyze of the reacting substance is between 5 mM and 500 mM.

6. The inspecting material of claim 1, wherein the reacting substance is a human serum albumin (HSA) detection reagent comprised in the inspecting material, the proportion of the human serum albumin (HSA) detection reagent comprised in the inspecting material is from 20% to 50%, wherein the efficiency is the best when the proportion is under 33%, and the detectable molar concentration of the analyze of the reacting substance is between 2 μ

M and 500 μ

M.

7. The inspecting material of claim 1, wherein the reacting substance is a bilirubin detection reagent comprised in the inspecting material, the proportion of the bilirubin detection reagent comprised in the inspecting material is from 10% to 50%, wherein the efficiency is the best when the proportion is under 20%, and the detectable concentration of the analyze of the reacting substance is between 10 mg/mL and 100 mg/mL.

8. The inspecting material of claim 1, wherein the reacting substance is an urobilinogen detection reagent comprised in the inspecting material, the proportion of the urobilinogen detection reagent comprised in the inspecting material is from 16% to 50%, wherein the efficiency is the best when the proportion is under 33%, and the detectable concentration of the analyze of the reacting substance is between 17 μ

M and 500 μ

M.

9. The inspecting material of claim 1, wherein the reacting substance is a ketone body detection reagent comprised in the inspecting material, the proportion of the ketone body detection reagent comprised in the inspecting material is from 20% to 66%, wherein the efficiency is the best when the proportion is under 50%, and the detectable concentration of the analyze of the reacting substance is between 0.5 mM and 200 mM.

10. The inspecting material of claim 1, wherein the reacting substance is a pH detection reagent comprised in the inspecting material, the proportion of the pH detection reagent comprised in the inspecting material is 16% to 50%, wherein the efficiency is the best when the proportion is under 20%, and the detectable pH value of the analyze of the reacting substance is between pH 4.0 and pH 10.0.

11. A sensor with an inspecting function, comprising:

a first carrier, having at least one inspecting area, a surface of the inspecting area disposed by the inspecting material of claim 1 to claim 10.

12. The sensor of claim 11, wherein the inspecting material comprises a lower gel layer, an upper gel layer, and an inspecting layer set between the upper gel layer and the lower gel layer, the lower gel layer contacted with the first carrier, the upper gel layer and the lower gel layer comprising the gel respectively, and the inspecting layer comprising the reacting substance.

13. The sensor of claim 12, wherein the inspecting material is formed by compiling the upper gel layer, the lower gel layer, and the inspecting layer.

14. The sensor of claim 11, wherein the inspecting material is doped on the surface of the inspecting area of the inspecting layer.

15. A patch sensor with a detection function, comprising:

a first carrier, having a first surface and a second surface, the first surface having at least one inspecting area, the surface of the inspecting area disposed by the inspecting material of claim 1 to claim 10; and

an attached film, having an upper surface with an adhesive material attached to the second surface of the first carrier.

16. The patch sensor of claim 15, wherein when the patch sensor is in use, the user can tear the attached film and make the patch sensor attach to a substance with the analyte to make the inspecting material on the first carrier contact with the analyte, the analyte penetrates into the gel to react with the reacting substance and makes the color of the reacting substance change to get the efficiency of the detection when the inspecting material is contacted with the analyte.

17. The patch sensor of claim 15, wherein the first carrier comprises a hydrophilic material and a hydrophobic material, and the inspecting area is made by the hydrophilic material.

18. The patch sensor of claim 15, wherein the inspecting material comprises a lower gel layer, an inspecting layer, and an upper gel layer, the inspecting layer is set between the upper gel layer and lower gel layer, the lower gel layer is contacted with the first carrier, the lower gel layer and the upper gel layer comprise the gel respectively, and the inspecting layer comprises the reacting substance.

19. The patch sensor of claim 17, wherein the first inspecting material is formed by compiling the upper gel layer, the inspecting layer, and the lower gel layer.

20. The patch sensor of claim 17, wherein the upper gel layer of the first inspecting layer has viscosity for attaching to the substance with the analyte.