METHOD OF PRODUCING PURIFIED STILBENE COMPOUNDS

• US 20160115110A1
• Filed: 10/16/2015
• Published: 04/28/2016
• Est. Priority Date: 10/17/2014
• Status: Active Grant

• Current Assignee: Morinaga & Company Limited
• Original Assignee: Morinaga & Company Limited
• Inventors: UMEHARA, Masahiro, KURITA, Ikuko, YANAE, Koji, SAI, Masahiko
• Granted Patent: US 10,730,815 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61K 31/05 Phenols cannabinoids A61K31/658
• CPC Class Codes: A61K 47/40 Cyclodextrins; Derivatives thereof
• CPC Class Codes: C07C 37/84 by crystallisation
• CPC Class Codes: C07C 39/21 with at least one hydroxy group on a non-condensed ring

Abstract

The present invention is directed to provide a precipitate obtained by adding γ-cyclodextrin to a liquid containing a stilbene compound. The precipitate according to the present invention is used as the precipitate obtained by adding γ-cyclodextrin to the liquid containing a stilbene compound.

Claims

1. A precipitate obtained by adding γ

-cyclodextrin to a liquid containing a stilbene compound.

2. The precipitate according to claim 1, wherein the precipitate has been separated from the liquid.

3. A method of purifying a stilbene compound from a liquid containing a stilbene compound, comprising the steps of:

adding γ

-cyclodextrin to the liquid to produce a precipitate; and

separating the precipitate from the liquid.

4. The method according to claim 3, wherein the purified stilbene compound is solid.

5. A method of producing a purified stilbene compound from a liquid containing a stilbene compound, comprising the steps of:

adding γ

-cyclodextrin to the liquid to produce a precipitate; and

separating the precipitate from the liquid.

6. The method according to claim 5, wherein the stilbene compound is piceatannol.

7. The method according to claim 5, wherein the liquid is a plant extract material.

8. The method according to claim 7, wherein the liquid is an extract material obtained from passion fruit seeds, rose myrtle, or stiff bottlebrush.

9. The method according to claim 5, wherein the liquid contains an organic solvent.

10. The method according to claim 9, wherein the organic solvent is alcohol.

11. The method according to claim 10, wherein the alcohol is ethanol.

12. The method according to claim 5, further comprising the step of adding water, anhydrous organic solvent, or water-containing organic solvent to the separated precipitate.