SYSTEMS AND METHODS FOR STEADY-STATE MAGNETIC RESONANCE FINGERPRINTING
First Claim
1. A method for generating a map of quantitative parameters of a subject using a magnetic resonance imaging (MRI) system, the method including steps comprising:
- (i) controlling the MRI system to;
(1) acquire magnetic resonance fingerprinting (MRF) data by fully sampling k-space, line-by-line, using a first flip angle and repetition time (TR);
(2) perform a delay to allow magnetization recover after reaching a steady state;
(3) acquire MRF data after the delay by fully sampling k-space, line-by-line, using a second flip angle and TR;
(4) repeat (1) through (3) to acquire the MRF data from a desired portion of the subject;
(ii) estimating quantitative parameters of the subject using the MRF data by comparing the MRF data to a dictionary database; and
(iii) generating a map of quantitative parameters of the subject using the estimated quantitative parameters of the subject and the MRF data.
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Abstract
Systems and methods for accelerating magnetic resonance fingerprinting (“MRF”) acquisitions are described. The method includes controlling the MRI system to acquire magnetic resonance fingerprinting (MRF) data from the subject by performing a gradient-echo pulse sequence. The pulse sequence includes maintaining residual transverse magnetization through a delay period performed between successive cycles of the pulse sequence. The delay period is selected to allow spins of different tissue types within the subject to evolve differently as a function of tissue parameters within the different tissue types during the delay period.
28 Citations
17 Claims
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1. A method for generating a map of quantitative parameters of a subject using a magnetic resonance imaging (MRI) system, the method including steps comprising:
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(i) controlling the MRI system to; (1) acquire magnetic resonance fingerprinting (MRF) data by fully sampling k-space, line-by-line, using a first flip angle and repetition time (TR); (2) perform a delay to allow magnetization recover after reaching a steady state; (3) acquire MRF data after the delay by fully sampling k-space, line-by-line, using a second flip angle and TR; (4) repeat (1) through (3) to acquire the MRF data from a desired portion of the subject; (ii) estimating quantitative parameters of the subject using the MRF data by comparing the MRF data to a dictionary database; and (iii) generating a map of quantitative parameters of the subject using the estimated quantitative parameters of the subject and the MRF data. - View Dependent Claims (2, 3, 4, 5)
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6. A method for generating a map of quantitative parameters of a subject using a magnetic resonance imaging (MRI) system, the method including steps comprising:
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(i) controlling the MRI system to acquire magnetic resonance fingerprinting (MRF) data from the subject by performing a gradient-echo pulse sequence that includes maintaining residual transverse magnetization through a delay period performed between successive cycles of the pulse sequence, wherein the delay period is selected to allow spins of different tissue types within the subject to evolve differently as a function of tissue parameters within the different tissue types during the delay period; (ii) estimating quantitative parameters of the subject using the MRF data by comparing the MRF data to a dictionary database; and (iii) generating a map of quantitative parameters of the subject using the estimated quantitative parameters of the subject and the MRF data. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13, 14)
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15. A magnetic resonance imaging (MRI) system, comprising:
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a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject arranged in the MRI system; a magnetic gradient system including a plurality of magnetic gradient coils configured to apply at least one magnetic gradient field to the polarizing magnetic field; a radio frequency (RF) system configured to apply an RF field to the subject and to receive magnetic resonance signals from the subject using a coil array; a computer system programmed to; control the MRI system to acquire magnetic resonance fingerprinting (MRF) data from the subject by performing a gradient-echo pulse sequence that includes maintaining residual transverse magnetization through a delay period performed between successive cycles of the pulse sequence, wherein the delay period is selected to allow spins of different tissue types within the subject to evolve differently as a function of tissue parameters within the different tissue types during the delay period; estimate quantitative parameters of the subject using the MRF data by comparing the MRF data to a dictionary database; and generate a map of quantitative parameters of the subject using the estimated quantitative parameters of the subject and the MRF data. - View Dependent Claims (16, 17)
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Specification