Discrimination of cheyne-stokes breathing patterns by use of oximetry signals
First Claim
1. A computer implemented method of detecting an occurrence of Cheyne-Stokes respiration in one or more programmed processors comprising:
- accessing blood gas data representing a measured blood gas signal;
determining a duration of one or more contiguous periods of changing saturation of a blood gas from the blood gas data; and
detecting the occurrence of Cheyne-Stokes respiration from a comparison of the determined duration and a threshold derived to differentiate saturation changes due to Cheyne-Stokes respiration and saturation changes due to obstructive sleep apnea.
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Accused Products
Abstract
Methods and apparatus provide Cheyne-Stokes respiration (“CSR”) detection based on a blood gas measurements such as oximetry. In some embodiments, a duration, such as a mean duration of contiguous periods of changing saturation or re-saturation occurring in an epoch taken from a processed oximetry signal, is determined. An occurrence of CSR may be detected from a comparison of the duration and a threshold derived to differentiate saturation changes due to CSR respiration and saturation changes due to obstructive sleep apnea. The threshold may be a discriminant function derived as a classifier by an automated training method. The discriminant function may be further implemented to characterize the epoch for CSR based on a frequency analysis of the oximetry data. Distance from the discriminant function may be utilized to generate probability values for the CSR detection.
23 Citations
27 Claims
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1. A computer implemented method of detecting an occurrence of Cheyne-Stokes respiration in one or more programmed processors comprising:
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accessing blood gas data representing a measured blood gas signal; determining a duration of one or more contiguous periods of changing saturation of a blood gas from the blood gas data; and detecting the occurrence of Cheyne-Stokes respiration from a comparison of the determined duration and a threshold derived to differentiate saturation changes due to Cheyne-Stokes respiration and saturation changes due to obstructive sleep apnea. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. An apparatus to detect an occurrence of Cheyne-Stokes breathing, the apparatus comprising:
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a memory for blood gas data representing a measured blood gas signal; and a processor coupled with the memory, the processor being configured (a) to determine a duration of one or more contiguous periods of changing saturation of a blood gas from the blood gas data and (b) to detect an occurrence of Cheyne-Stokes respiration from a comparison of the determined duration and a threshold derived to differentiate saturation changes due to Cheyne-Stokes respiration and saturation changes due to obstructive sleep apnea. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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27. An apparatus for detecting an occurrence of Cheyne-Stokes respiration comprising:
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means for accessing blood gas data representing a measured blood gas signal; means for determining a duration of one or more contiguous periods of changing saturation of a blood gas from the blood gas data; and means for detecting the occurrence of Cheyne-Stokes respiration from a comparison of the determined duration and a threshold derived to differentiate saturation changes due to Cheyne-Stokes respiration and saturation changes due to obstructive sleep apnea.
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Specification