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METHDS AND COMPOSITIONS FOR REPLICATION OF THREOSE NUCLEIC ACIDS

  • US 20160138063A1
  • Filed: 01/02/2014
  • Published: 05/19/2016
  • Est. Priority Date: 01/04/2013
  • Status: Abandoned Application
First Claim
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1. A method for synthesizing a threose nucleic acid polymer, comprising:

  • contacting a single stranded DNA template hybridized to a primer with a DNA polymerase comprising an amino acid sequence at least 95% identical to the amino acid sequence of SEQ ID NO;

    1 in the presence of tTTP, tGTP, tATP; and

    (i) dCTP;

    or (ii) a combination of tCTP and dCTP; and

    incubating at a temperature suitable for polymerization by the DNA polymerase to obtain a threose nucleic acid.

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