NEURAL PROBE WITH OPTICAL STIMULATION CAPABILITY
First Claim
1. A neural probe, comprising:
- a probe body;
a shank extending from the probe body to a tip;
a light-emitting diode (LED) light source attached to the tip for providing neuron-affecting light at said tip; and
one or more recording electrodes attached to said tip for receiving electrical responses to the neuron-affecting light.
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Accused Products
Abstract
A neural probe is disclosed for optically stimulating or silencing neurons and recording electrical responses to the stimulus. Using patterning techniques, an integral optical waveguide may be fabricated on the probe for transmitting neuron-affecting light from a light source to a probe tip. The probe tip may include one or more electrodes to receive electrical responses from stimulated neurons for recording or further processing. According to various embodiments, the disclosed neural probes may utilize multiple light sources simultaneously, switch between multiple light sources, or utilize a single light source to stimulate or silence multiple neuron locations simultaneously via multiple probe tips or via multiple light-emitting sites located along the length of the probe. Neural probes are thereby provided that have sufficient spatial resolution to accurately target, stimulate, and record the reaction of neurons, or as few as a single neuron, utilizing a slim, compact structure.
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Citations
22 Claims
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1. A neural probe, comprising:
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a probe body; a shank extending from the probe body to a tip; a light-emitting diode (LED) light source attached to the tip for providing neuron-affecting light at said tip; and one or more recording electrodes attached to said tip for receiving electrical responses to the neuron-affecting light. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A neural probe, comprising:
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a probe body; a shank extending from the probe body to a tip; a light-emitting diode (LED) light source patterned on the shank for providing neuron-affecting light; and one or more recording electrodes attached to said tip for receiving electrical responses to the neuron-affecting light. - View Dependent Claims (19, 20, 21)
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22. A neural probe, comprising:
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a probe body; a shank extending from the probe body to a tip and having an outer perimeter; a light-emitting diode (LED) light source patterned at the tip for providing neuron-affecting light at said tip; and a plurality of recording electrodes for receiving electrical responses to the neuron-affecting light, wherein the plurality of recording electrodes are attached to said tip such that they are closer to the outer perimeter of the shank than the LED light source.
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Specification