MULTIPLEXED PATHLENGTH RESOLVED NONINVASIVE ANALYZER APPARATUS WITH DYNAMIC OPTICAL PATHS AND METHOD OF USE THEREOF
First Claim
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1. A method for noninvasively determining an analyte concentration of a person, comprising the steps of:
- providing a near-infrared analyzer, comprising;
at least one near-infrared source;
a detector; and
a photon transport system configured to direct photons from said source, via a sample illumination zone, to said detector via both a detection zone and a face of an analyzer-sample optical interface;
dynamically changing, within a time window of data collection for a single analyte concentration determination, a mean radial illumination position of incident light from said near-infrared source relative to a center of the detection zone of said analyzer-sample optical interface, said step of dynamically changing further comprising;
directing the photons, during a first time period of the time window, to a first arc of illumination optics at a first range of radial distances from the detection zone; and
directing the photons, during a second time period of the time window, to a second arc of illumination optics at a second range of radial distances from the detection zone,wherein at said analyzer-sample optical interface none of said first range of radial distances overlap any of said second range of radial distances.
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Abstract
A noninvasive analyzer apparatus and method of use thereof is described comprising a near-infrared source, a detector, and a photon transport system configured to direct photons from the source to the detector via an analyzer-sample optical interface. The photon transport system includes a dynamically position light directing unit used to, within a measurement time period for a single analyte concentration determination, change any of: radius, energy, intensity, position, incident angle, solid angle, and/or depth of penetration of a beam of photons entering skin of a subject.
10 Citations
20 Claims
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1. A method for noninvasively determining an analyte concentration of a person, comprising the steps of:
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providing a near-infrared analyzer, comprising; at least one near-infrared source; a detector; and a photon transport system configured to direct photons from said source, via a sample illumination zone, to said detector via both a detection zone and a face of an analyzer-sample optical interface; dynamically changing, within a time window of data collection for a single analyte concentration determination, a mean radial illumination position of incident light from said near-infrared source relative to a center of the detection zone of said analyzer-sample optical interface, said step of dynamically changing further comprising; directing the photons, during a first time period of the time window, to a first arc of illumination optics at a first range of radial distances from the detection zone; and directing the photons, during a second time period of the time window, to a second arc of illumination optics at a second range of radial distances from the detection zone, wherein at said analyzer-sample optical interface none of said first range of radial distances overlap any of said second range of radial distances. - View Dependent Claims (2, 3, 4, 5, 8, 9, 10, 11, 12, 13, 20)
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6. (canceled)
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7. (canceled)
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14. An apparatus for noninvasively determining an analyte concentration of a person, comprising:
a near-infrared analyzer, comprising; at least one near-infrared source; a detector; and a photon transport system configured to direct photons from said source, via a sample illumination zone, to said detector via both a detection zone and a face of an analyzer-sample optical interface, said photon transport system further comprising; means for dynamically changing, within a time period of data collection for a single analyte concentration determination, a radial illumination position of incident light from said near-infrared source relative to a center of the detection zone of said analyzer-sample optical interface, said means for dynamically changing the radial illumination position comprising a dynamically positioned optic system; a first arc of illumination optics configured to direct the photons, during a first time period of the time window, to a first range of radial distances from the detection zone; and a second arc of illumination optics configured to direct the photons, during a second time period of the time window, to a second range of radial distances from the detection zone, wherein at said analyzer-sample optical interface none of said first range of radial distances overlap than any of said second range of radial distances. - View Dependent Claims (16, 17, 18, 19)
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15. (canceled)
Specification