SIMULTANEOUS ACQUISITION OF BIOMETRIC DATA AND NUCLEIC ACID

• US 20160154990A1
• Filed: 09/25/2015
• Published: 06/02/2016
• Est. Priority Date: 09/16/2011
• Status: Abandoned Application

• Current Assignee: Life Technologies Corporation (Thermo Fisher Scientific Incorporated)
• Original Assignee: Life Technologies Corporation (Thermo Fisher Scientific Incorporated)
• Inventors: Harrold, Michael, Hennessy, Lori, Lagace, Robert
• Application Number:
  US14/865,079
• Publication Number:
  US 20160154990A1
• Time in Patent Office: Days
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 5/1172 using fingerprinting
• CPC Class Codes: A61B 5/1174 using footprinting
• CPC Class Codes: A61B 5/1176 Recognition of faces
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150267 Modular design or construction, i.e. subunits are assembled separately before being joined together or the device comprises interchangeable or detachable modules
• CPC Class Codes: A61B 5/150305 Packages specially adapted for piercing devices or blood sampling devices kits for diabetes A61M5/003; packaging in general B65D
• CPC Class Codes: A61B 5/150396 Specific tip design, e.g. for improved penetration characteristics
• CPC Class Codes: A61B 5/150404 Specific design of proximal end
• CPC Class Codes: A61B 5/150419 comprising means for capillary action
• CPC Class Codes: A61B 5/150427 Specific tip design, e.g. for improved penetration characteristics
• CPC Class Codes: A61B 5/150435 Specific design of proximal end
• CPC Class Codes: A61B 5/150511 Details of construction of shaft
• CPC Class Codes: A61B 5/150748 Having means for aiding positioning of the piercing device at a location where the body is to be pierced means for aiding positioning of devices for bringing media into the body A61M5/427, locating blood vessels A61B5/489
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/150786 Optical identification systems, e.g. bar codes, colour codes
• CPC Class Codes: A61B 5/150847 : Communication to or from blood sampling device transmitting measured data A61B5/0002
• CPC Class Codes: A61B 5/150954 : Means for the detection of operative contact with patient, e.g. by temperature sensitive sensor
• CPC Class Codes: A61B 5/15109 : Fully automatically triggered, i.e. the triggering does not require a deliberate action by the user, e.g. by contact with the patient's skin
• CPC Class Codes: A61B 5/1519 : comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/157 : Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: G05B 1/00 : Comparing elements, i.e. elements for effecting comparison directly or indirectly between a desired value and existing or anticipated values
• CPC Class Codes: G06V 2201/04 : Recognition of patterns in DNA microarrays
• CPC Class Codes: G06V 40/12 : Fingerprints or palmprints
• CPC Class Codes: G06V 40/1359 : Extracting features related to ridge properties; Determining the fingerprint type, e.g. whorl or loop
• CPC Class Codes: G06V 40/1382 : Detecting the live character of the finger, i.e. distinguishing from a fake or cadaver finger
• CPC Class Codes: G06V 40/70 : Multimodal biometrics, e.g. combining information from different biometric modalities

Abstract

Disclosed are devices and methods for collection and analyzing biological samples containing nucleic acid in conjunction with collecting at least one ridge and valley signature of a test subject, while keeping the sample and signature associated with each other. Such devices and methods are used in forensic, human identification, screening, and access control technologies to rapidly process an individual'"'"'s identity or determine the identity of an individual.

Claims

1. A system for collecting a biological sample comprising at least one nucleic acid and at least one ridge and valley signature of an individual, the system comprising:

a biological collection component comprising an epidermal puncturing device operationally connected to a presence sensor, wherein the epidermal puncturing device is configured to be activated to penetrate the epidermis of the individual and to retract, thereby extracting the biological sample; and

at least a first imaging component configured to collect the at least one ridge and valley signature, wherein the at least first imaging component comprises i) a platen configured to receive an appendage of the individual, and ii) a presence sensor configured to a) detect when the appendage is placed in proximity to the platen, and b) activate the epidermal puncturing device to extract the biological sample.

2. The system of claim 1, wherein the presence sensor is a pressure sensor, optical sensor, electronic sensor, capacitive sensor or thermal sensor.

3. The system of claim 1, wherein the presence sensor is located a) parallel to the length of a digit, palm, sole, hand or foot;

b) perpendicular to the distal end of the digit;

or c) resides below the platen, and wherein the presence sensor activates the epidermal puncturing device to a position above the plane of the platen thereby penetrating the epidermis of the subject.

4. The system of claim 1, wherein the at least first imaging component is an optical scanner or a capacitance scanner.

5. The system of claim 4, wherein the optical scanner is an array of a plurality of light emitting diodes or a multispectral illuminator.

6. The system of claim 1, further comprising a processor configured to transmit the ridge and valley signature of the individual to at least one database comprising ridge and valley signatures selected from the group consisting of a forensic, criminal, identity, child identity, missing persons, immigration, department of motor vehicles, terrorist, paternity, arrestee, convict database, access control and any combination thereof.

7. The system of claim 1, further comprising an identifier configured to associate the biological sample of the individual with the at least one ridge and valley signature of the individual, wherein the identifier is alphanumeric, graphical, magnetic, or electromagnetic.

8. The system of claim 7, wherein the identifier is a barcode.

9. The system of claim 1, wherein the epidermal puncturing device comprises:

an anterior portion configured to penetrate the epidermis, wherein the anterior portion is selected from the group of a needle, a microneedle, and a lancet; and

a posterior portion configured to be operationally connected to the presence sensor.

10. The system of claim 9, wherein the anterior portion of the epidermal puncturing device further comprises a beveled opening.

11. The system of claim 9, wherein the anterior portion of the epidermal puncturing device further comprises a lumen.

12. The system of claim 9, wherein the anterior portion of the epidermal puncturing device is removable.

13. The system of claim 9, wherein the biological sample is conducted for collection to a) a collection substrate positioned perpendicular to and surrounding the posterior portion of the epidermal puncturing device;

b) a collection substrate positioned within a lumen of the epidermal puncturing device;

or c) a lumen of the epidermal puncturing device.

14. The system of claim 13, wherein the system is configured to apply vacuum to the epidermal puncturing device to assist in collecting the biological sample.

15. The system of claim 1, wherein:

when the epidermis penetrated by the epidermal puncturing device is located on a finger or a hand, then the at least one ridge and valley signature is obtained from at least one finger or the palm;

or

when the epidermis penetrated by the epidermal puncturing device is located on a toe or a foot, then the at least one ridge and valley signature is obtained from the sole of the foot.

16. The system of claim 1, wherein the at least one ridge and valley signature is obtained from at least one finger.

17. A method of identifying an individual by collecting a biological sample comprising at least one nucleic acid sample and at least one ridge and valley signature of a individual, comprising the steps of:

providing an imaging component having a platen surface and a presence sensor wherein the platen surface is configured to permit an energy wave to penetrate the platen;

positioning an appendage of an individual in proximity to the platen and the presence sensor, wherein when the presence sensor detects the proximity of the appendage then the presence sensor activates an epidermal puncturing device to contact the appendage and to penetrate the epidermis of the appendage;

collecting the biological sample to the epidermal puncturing device; and

collecting the at least one ridge and valley signature imaged by the energy wave, wherein the signature is collected electronically.

18. The method of claim 17, wherein the ridge and valley signature is collected electronically and wherein the presence sensor detects the proximity of the appendage via pressure, an optical signal, an electronic signal, capacitance or temperature and wherein the imaging component is an optical scanner or a capacitance scanner.

19-30. -30. (canceled)

31. A device for collecting a biological sample comprising at least one nucleic acid from an individual comprising:

an anterior portion having a lumen, a first end configured to penetrate at least into a dermal layer of the individual, and a second end;

a posterior portion configured to be operatively connected to a presence sensor, wherein the posterior portion optionally has a collection substrate surrounding or inside a lumen of the posterior portion; and

further wherein the second end of the anterior portion is connected to the posterior portion and wherein the first end of the anterior portion is pointed.

32. (canceled)

33. A kit comprising the device of claim 32, and optionally, instructions for use.