FILM FOR BIOSENSORS AND PREPARATION METHOD
First Claim
1. An organosilicon polymer, raw materials of the organosilicon polymer comprising:
- 100 parts by weight of at least one active organosilane, wherein the active organosilane comprises one or more functional groups;
at least one curing agent;
from 0 to 100 parts by weight of at least one hydrophilic copolymer, wherein the hydrophilic copolymer is a hydrophilic polymer with one or more functional groups; and
from 0 to 20 parts by weight of at least one modifier; and
from 0 to 10 parts by weight of at least one fillerwherein the curing agent is a chain extender with two degrees of functionality or a cross-linking agent with three or more functional groups, and the amount of the curing agent is determined as follows;
if the curing agent is a chain extender, the number of moles of the curing agent functional groups is the sum of the number of moles of the functional groups of the active organosilane and the number of moles of the functional groups of the hydrophilic copolymer, andif the curing agent is a cross-linking agent, the number of moles of the curing agent functional groups is 1.05 to 1.20 times the sum of the number of moles of the functional groups of the active organosilane and the number of moles of the functional groups of the hydrophilic copolymer.
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Abstract
The present invention relates to the field of film materials for biosensors, in particular to a film for biosensors and a preparation method. Provided is an organosilicon polymer, the raw materials thereof comprising the following components: at least one active organosilane, at least one curing agent, at least one optional hydrophilic copolymer and at least one optional regulator and/or filling. The membrane prepared from the provided organosilicon polymer has outstanding oxygen permeability and is adjustable in water absorption rate, and can put regulation and restriction on the diffusion of analytes (e.g. glucose) and interferents (e.g. acetaminophen). Meanwhile, the provided organosilicon polymer film also has indispensable physical strength and superior biocompatibility, and can serve as a multifunctional polymer film material for biosensors, such as anti-interference layer, analyte regulating layer and biocompatible layer.
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Citations
23 Claims
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1. An organosilicon polymer, raw materials of the organosilicon polymer comprising:
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100 parts by weight of at least one active organosilane, wherein the active organosilane comprises one or more functional groups; at least one curing agent; from 0 to 100 parts by weight of at least one hydrophilic copolymer, wherein the hydrophilic copolymer is a hydrophilic polymer with one or more functional groups; and from 0 to 20 parts by weight of at least one modifier; and from 0 to 10 parts by weight of at least one filler wherein the curing agent is a chain extender with two degrees of functionality or a cross-linking agent with three or more functional groups, and the amount of the curing agent is determined as follows; if the curing agent is a chain extender, the number of moles of the curing agent functional groups is the sum of the number of moles of the functional groups of the active organosilane and the number of moles of the functional groups of the hydrophilic copolymer, and if the curing agent is a cross-linking agent, the number of moles of the curing agent functional groups is 1.05 to 1.20 times the sum of the number of moles of the functional groups of the active organosilane and the number of moles of the functional groups of the hydrophilic copolymer. - View Dependent Claims (3, 6, 7, 8, 9, 10, 12, 14, 15, 16, 17, 20, 21, 22, 23)
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2. (canceled)
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4. (canceled)
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5. (canceled)
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11. (canceled)
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13. (canceled)
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18. (canceled)
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19. (canceled)
Specification