DEVICES, SYSTEMS, AND METHODS FOR DETECTING ANOMALOUS CARDIAC WAVEFORMS AND MAKING PHYSIOLOGIC MEASUREMENT CALCULATIONS

• US 20160157785A1
• Filed: 12/07/2015
• Published: 06/09/2016
• Est. Priority Date: 12/08/2014
• Status: Active Application

• Current Assignee: Volcano Corporation (Koninklijke Philips N.V.)
• Original Assignee: Volcano Corporation (Koninklijke Philips N.V.)
• Inventors: Merritt, Fergus, Tochterman, Andrew, Unser, John, Anderson, David
• Application Number:
  US14/961,601
• Publication Number:
  US 20160157785A1
• Time in Patent Office: Days
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

Devices, systems, and methods automatically detecting anomalous waveforms and eliminating these waveforms from physiologic measurements are disclosed. For example, in some instances a method includes collecting a pressure data from an intravascular device positioned within the vessel of the patient, the pressure data including a pressure waveform for each cardiac cycle of the patient; comparing the pressure waveform for each cardiac cycle of the patient to a reference pressure waveform to identify an anomalous pressure waveform; and calculating a pressure ratio utilizing the pressure data from the intravascular device, wherein data from the anomalous pressure waveform is excluded from the calculation.

Claims

1. A method of evaluating a vessel of a patient, comprising:

collecting pressure data from an intravascular device positioned within the vessel of the patient, the pressure data including a pressure waveform for each cardiac cycle of the patient;

comparing the pressure waveform for each cardiac cycle of the patient to a reference pressure waveform to identify an anomalous pressure waveform; and

calculating a pressure ratio utilizing the pressure data from the intravascular device, wherein data from the anomalous pressure waveform is either excluded from the calculation or modified for use in the calculation.

2. The method of claim 1, wherein the reference pressure waveform is based on a previously recorded set of pressure waveforms of the patient.

3. The method of claim 2, wherein the reference pressure waveform remains fixed during a procedure.

4. The method of claim 2, wherein the reference pressure waveform varies during a procedure.

5. The method of claim 4, wherein the reference pressure waveform is based on n previous pressure waveforms obtained during the procedure.

6. The method of claim 1, wherein the reference pressure waveform is selected from a database of available pressure waveforms.

7. The method of claim 1, wherein comparing the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform includes comparing a total cycle duration.

8. The method of claim 1, wherein comparing the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform includes comparing at least one of a mean pressure, a range between a maximum pressure and a minimum pressure, or a slope of a portion of the waveform.

9. The method of claim 1, wherein comparing the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform includes comparing a distal pressure waveform to a proximal pressure waveform.

10. The method of claim 1, further comprising identifying a group of anomalous waveforms based on comparing the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform.

11. A system for evaluating a vessel of a patient, comprising:

at least one pressure-sensing intravascular device sized and shaped for positioning within the vessel of the patient; and

a processing system in communication with the at least one pressure-sensing device, the processing system configured to;

collect pressure data from the at least one pressure-sensing intravascular device, the pressure data including a pressure waveform for each cardiac cycle of the patient;

compare the pressure waveform for each cardiac cycle of the patient to a reference pressure waveform to identify an anomalous pressure waveform;

calculate a pressure ratio utilizing the pressure data from the intravascular device, wherein data from the anomalous pressure waveform is excluded from the calculation.

12. The system of claim 11, wherein the reference pressure waveform is based on a previously recorded set of pressure waveforms of the patient.

13. The system of claim 12, wherein the reference pressure waveform remains fixed during a procedure.

14. The system of claim 12, wherein the reference pressure waveform varies during a procedure.

15. The system of claim 14, wherein the reference pressure waveform is based on n previous pressure waveforms obtained during the procedure.

16. The system of claim 11, wherein the reference pressure waveform is selected from a database of available pressure waveforms.

17. The system of claim 11, wherein processing system is configured to compare the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform by comparing a total cycle length.

18. The system of claim 11, wherein processing system is configured to compare the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform by comparing at least one of a mean pressure, a range between a maximum pressure and a minimum pressure, or a slope of a portion of the waveform.

19. The system of claim 11, wherein processing system is configured to compare the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform by comparing a distal pressure waveform to a proximal pressure waveform.

20. The system of claim 11, wherein processing system is further configured to identify a group of anomalous waveforms based on comparing the pressure waveform for each cardiac cycle of the patient to the reference pressure waveform.