DEVICE FOR TREATING A CUTANEOUS ULCER

• US 20160158543A1
• Filed: 07/15/2014
• Published: 06/09/2016
• Est. Priority Date: 07/15/2013
• Status: Active Grant

• Current Assignee: Centre Hospitalier Universitaire de Grenoble, Universite Joseph Fourier
• Original Assignee: Centre Hospitalier Universitaire de Grenoble, Université Grenoble Alpes
• Inventors: CRACOWSKI, Jean-Luc, ROUSTIT, Matthieu, BLAISE, Sophie
• Granted Patent: US 10,874,856 B2
• Time in Patent Office: Days
• CPC Class Codes: A61F 13/00063 comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic drug delivery dressings A61K9/70; chemical aspect of the additives A61L15/00
• CPC Class Codes: A61F 2013/00285 medication confinement
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

A device treats a region of the body of a patient having a cutaneous ulcer, including:

• • a hydrogel, hydrocolloid, hydrocellular or hydrofiber primary dressing, impregnated with treprostinil, that can be shaped to the contours of the region to be treated,
  • a so-called “active” electrode in contact with the primary dressing,
  • a so-called “passive” electrode at a distance from the active electrode,
  • a DC generator, the terminals of which are connected to the electrodes, the cathode and the anode respectively forming the active electrode and the passive electrode for iontophoresis, so as to cause treprostinil to migrate by cathodal iontophoresis into the region to be treated.

Claims

1. A device for treating a region of the body of a patient having a cutaneous ulcer, comprising:

a hydrogel, hydrocolloid, hydrocellular or hydrofiber primary dressing, impregnated with treprostinil, that can be shaped to the contours of the region to be treated;

a first electrode, in contact with the primary dressing;

a second electrode, at a distance from the first electrode;

a DC generator, the terminals of which are connected to the first and second electrodes, the cathode and the anode respectively forming an active electrode and a passive electrode for iontophoresis, so as to cause treprostinil to migrate by cathodal iontophoresis into the region to be treated.

2. The device according to claim 1, wherein the concentration of treprostinil impregnating the primary dressing is between 0.25 mM and 25 mM.

3. The device according to claim 1, wherein the active electrode includes conductive ink deposited on the primary dressing.

4. The device according to claim 1, wherein the DC generator is adapted to generate direct current having a strength between 20 μ

A/cm² and 100 μ

A/cm².

5. The device according to claim 1, wherein said DC generator is borne by a support adapted to be attached to the patient'"'"'s skin.

6. The device according to claim 1, wherein the DC generator is integral with the primary dressing and the active and passive electrodes.

7. The device according to claim 1, further comprising a secondary dressing that is adapted to be shaped to the contours of the region to be treated, the secondary dressing supporting the primary dressing in contact with the first electrode, the second electrode and the DC generator.

8. The device according to claim 1, further comprising a module comprising the second electrode and the DC generator, the module being distinct from the primary dressing and adapted to be connected to the first electrode.

9. The device according to claim 1, wherein the surface area of the primary dressing is between 5 cm² and 100 cm².

10. The device according to claim 1, which is in a form adapted to be slipped onto the patient'"'"'s finger, the primary dressing and the first electrode being adapted to be shaped to the pad of the finger and the second electrode is adapted to be shaped to the outer face of the finger opposite the pad.

11. The device according to claim 1, further comprising a secondary dressing that is adapted to be shaped to the contours of the region to be treated, intended to cover the primary dressing.