Noninvasive Blood Glucose Measurement Method and Apparatus

• US 20160174853A1
• Filed: 12/21/2015
• Published: 06/23/2016
• Est. Priority Date: 12/19/2014
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: CHO, Chul-ho, LEE, Seung-min, KIM, Kwang-bok, CHO, Seong-je, LEE, Jeong-gun, JUNG, Sun-tae, CHO, Jae-geol
• Granted Patent: US 10,835,130 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 10/0051 for taking saliva or sputum samples devices for receiving spittle A61J9/00
• CPC Class Codes: A61B 10/0064 for taking sweat or sebum samples measuring sweat production A61B5/4266
• CPC Class Codes: A61B 10/007 for taking urine samples measuring urological functions A61B5/20; genital receptacles A61F5/451; urinals for bed-ridden persons A61G9/006
• CPC Class Codes: A61B 2010/0067 Tear or lachrymal fluid
• CPC Class Codes: A61B 3/101 for examining the tear film
• CPC Class Codes: A61B 3/112 for measuring diameter of pupils
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0024 for multiple sensor units attached to the patient, e.g. using a body or personal area network
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0533 Measuring galvanic skin response
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/112 Gait analysis
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4035 Evaluating the autonomic nervous system
• CPC Class Codes: A61B 5/4261 Evaluating exocrine secretion production A61B3/101 takes precedence
• CPC Class Codes: A61B 5/4266 : sweat secretion
• CPC Class Codes: A61B 5/4277 : saliva secretion
• CPC Class Codes: A61B 5/443 : Evaluating skin constituents, e.g. elastin, melanin, water
• CPC Class Codes: A61B 5/7278 : Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

A blood glucose measurement apparatus includes: a control unit configured to determine a user'"'"'s blood glucose level based on a concentration of body fluid secreted from the user; and a biometric information acquisition unit configured to acquire biometric information indicating a status of a user'"'"'s autonomic nervous system. The control unit is configured to correct the determined blood glucose level based on the biometric information.

Claims

1. A blood glucose measurement apparatus comprising:

a control unit configured to determine a user'"'"'s blood glucose level based on a concentration of body fluid secreted from the user; and

a biometric information acquisition unit configured to acquire biometric information indicating a status of a user'"'"'s autonomic nervous system,

wherein the control unit is configured to correct the determined user'"'"'s blood glucose level based on the biometric information.

2. The blood glucose measurement apparatus of claim 1, wherein the control unit is configured to determine the status of the autonomic nervous system based on the biometric information, determine a secretion velocity of the body fluid based on the determined status of the autonomic nervous system, and correct the determined user'"'"'s blood glucose level based on the determined secretion velocity of the body fluid.

3. The blood glucose measurement apparatus of claim 1, wherein the body fluid includes at least one of a user'"'"'s sweat, tear, saliva, and urine.

4. The blood glucose measurement apparatus of claim 1, wherein the status of the autonomic nervous system includes an activity degree of at least one of a user'"'"'s sympathetic nerve and parasympathetic nerve.

5. The blood glucose measurement apparatus of claim 1, wherein the biometric information indicating the status of the autonomic nervous system includes at least one of a user'"'"'s heart rate, a user'"'"'s galvanic skin response, a contraction degree of a user'"'"'s blood vessel, a size of a user'"'"'s pupil, an amount of a user'"'"'s sweat, an amount of a user'"'"'s tear, an amount of a user'"'"'s saliva, and a user'"'"'s body temperature.

6. The blood glucose measurement apparatus of claim 1, wherein the biometric information acquisition unit comprises a communication unit configured to receive the biometric information indicating the status of the user'"'"'s autonomic nervous system from a sensor attached to the user.

7. A blood glucose measurement apparatus comprising:

a control unit configured to determine a user'"'"'s blood glucose level based on a concentration of biomarker gas in a user'"'"'s expiration; and

a biometric information acquisition unit configured to acquire biometric information indicating a user'"'"'s motion quantity,

wherein the control unit is configured to correct the determined user'"'"'s blood glucose level based on the biometric information.

8. The blood glucose measurement apparatus of claim 7, wherein the biomarker gas is a gas that is discharged through the user'"'"'s expiration when a user'"'"'s body fat is decomposed.

9. The blood glucose measurement apparatus of claim 7, wherein the biometric information indicating the user'"'"'s motion quantity comprises at least one of a user'"'"'s step count, a user'"'"'s moving speed, a user'"'"'s heart rate, a users'"'"' skin hydration, and a user'"'"'s body temperature.

10. The blood glucose measurement apparatus of claim 7, wherein the control unit is configured to determine a user'"'"'s motion quantity per unit time based on the biometric information and correct the determined user'"'"'s blood glucose level based on the determined motion quantity per unit time.

11. A blood glucose measurement method comprising:

determining a user'"'"'s blood glucose level based on a concentration of body fluid secreted from the user;

acquiring biometric information indicating a status of a user'"'"'s autonomic nervous system; and

correcting the determined user'"'"'s blood glucose level based on the biometric information.

12. The blood glucose measurement method of claim 11, wherein the correcting of the determined user'"'"'s blood glucose level based on the biometric information comprises:

determining the status of the autonomic nervous system based on the biometric information;

determining a secretion velocity of the body fluid based on the determined status of the autonomic nervous system; and

correcting the determined user'"'"'s blood glucose level based on the determined secretion velocity of the body fluid.

13. The blood glucose measurement method of claim 11, wherein the body fluid includes at least one of a user'"'"'s sweat, tear, saliva, and urine.

14. The blood glucose measurement method of claim 11, wherein the status of the autonomic nervous system includes an activity degree of at least one of a user'"'"'s sympathetic nerve and parasympathetic nerve.

15. The blood glucose measurement method of claim 11, wherein the biometric information indicating the status of the autonomic nervous system includes at least one of a user'"'"'s heart rate, a user'"'"'s galvanic skin response, a contraction degree of a user'"'"'s blood vessel, a size of a user'"'"'s pupil, an amount of a user'"'"'s sweat, an amount of a user'"'"'s tear, an amount of a user'"'"'s saliva, and a user'"'"'s body temperature.

16. The blood glucose measurement method of claim 11, wherein the acquiring of the biometric information indicating the status of the user'"'"'s autonomic nervous system comprises receiving the biometric information indicating the status of the user'"'"'s autonomic nervous system from a sensor attached to the user.

17. A blood glucose measurement method comprising:

determining a user'"'"'s blood glucose level based on a concentration of biomarker gas in a user'"'"'s expiration;

acquiring biometric information indicating a user'"'"'s motion quantity; and

correcting the determined user'"'"'s blood glucose level based on the biometric information.

18. The blood glucose measurement method of claim 17, wherein the biomarker gas is a gas that is discharged through the user'"'"'s expiration when a user'"'"'s body fat is decomposed.

19. The blood glucose measurement method of claim 17, wherein the biometric information indicating the user'"'"'s motion quantity comprises at least one of a user'"'"'s step count, a user'"'"'s moving speed, a user'"'"'s heart rate, a user'"'"'s skin hydration, and a user'"'"'s body temperature.

20. The blood glucose measurement method of claim 17, wherein the correcting of the determined user'"'"'s blood glucose level based on the biometric information comprises:

determining the user'"'"'s motion quantity per unit time based on the biometric information; and

correcting the determined blood glucose level based on the determined motion quantity per unit time.