INFUSION DEVICES AND RELATED METHODS AND SYSTEMS FOR AUTOMATIC ALERT CLEARING

• US 20160174911A1
• Filed: 12/19/2014
• Published: 06/23/2016
• Est. Priority Date: 12/19/2014
• Status: Active Application

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: Myers, Jeffrey C., Palerm, Cesar C.
• Granted Patent: US 10,265,031 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of alerting a user associated with an infusion device delivering fluid to the body of the user involves obtaining a first value for a physiological condition being influenced by the fluid, determining a metric corresponding to a future physiological condition of the user based at least in part on the first value, and automatically generating a first alert based on the metric. After automatically generating the first alert, the method continues by obtaining a second value for the physiological condition of the user and automatically clearing the first alert based at least in part on the second value.

Claims

1. A method of alerting a user, the method comprising:

obtaining a first value for a physiological condition in a body of the user, the physiological condition being influenced by a fluid delivered by an infusion device;

determining a metric corresponding to a future physiological condition of the user based at least in part on the first value;

automatically generating a first alert based on the metric; and

after automatically generating the first alert;

obtaining a second value for the physiological condition of the user; and

automatically clearing the first alert based at least in part on the second value.

2. The method of claim 1, further comprising determining an updated metric corresponding to the future physiological condition of the user based at least in part on the second value, wherein automatically clearing the first alert comprises automatically clearing the first alert based on the updated metric.

3. The method of claim 2, wherein:

obtaining the first value comprises obtaining a first measurement value for the physiological condition from a body of the user at a first time;

determining the metric comprises determining a homeostasis metric based at least in part on the first measurement value;

obtaining the second value comprises obtaining a second measurement value for the physiological condition from the body of the user at a second time after the first time;

the updated metric comprises an updated value for the homeostasis metric determined based at least in part on the second measurement value; and

automatically clearing the first alert comprises automatically clearing the first alert based on the updated value.

4. The method of claim 3, further comprising:

obtaining a first amount of active fluid in the body of the user at the first time, wherein determining the homeostasis metric comprises determining a value for the homeostasis metric based at least in part on the first measurement value and the first amount of active fluid; and

obtaining a second amount of active fluid in the body of the user at the second time, wherein determining the updated metric comprises determining the updated value for the homeostasis metric based at least in part on the second measurement value and the second amount of active fluid.

5. The method of claim 4, wherein:

automatically generating the first alert based on the metric comprises generating a user notification when the value for the homeostasis metric is greater than an alert threshold; and

automatically clearing the first alert comprises automatically clearing the first alert when the second value is less than the alert threshold.

6. The method of claim 2, the fluid comprising insulin influencing a glucose level in a body of the user, wherein:

obtaining the first value comprises obtaining a first glucose measurement value from the body of the user at a first time;

determining the metric comprises determining a predicted glucose value based at least in part on the first glucose measurement value;

automatically generating the first alert comprises automatically providing the first alert when the predicted glucose value violates a first alerting threshold;

obtaining the second value comprises obtaining a second glucose measurement value from the body of the user at a second time after the first time;

determining the updated metric comprises determining an updated predicted glucose value based at least in part on the second glucose measurement value; and

automatically clearing the first alert comprises automatically clearing the first alert when the updated predicted glucose value does not violate the first alerting threshold.

7. The method of claim 1, the fluid comprising insulin influencing a glucose level in a body of the user, wherein:

obtaining the first value comprises obtaining a first glucose measurement value from the body of the user at a first time;

determining the metric comprises determining a homeostasis metric based at least in part on the first glucose measurement value;

obtaining the second value comprises obtaining a second glucose measurement value from the body of the user at a second time after the first time; and

automatically clearing the first alert comprises automatically clearing the first alert when the second glucose measurement value violates an alert threshold.

8. The method of claim 7, wherein:

determining the homeostasis metric comprises determining a recommended correction bolus amount based on the first glucose measurement value; and

automatically clearing the first alert comprises automatically clearing the first alert when the second glucose measurement value is greater than a hyperglycemic alert threshold.

9. The method of claim 8, wherein automatically clearing the first alert comprises automatically providing a hyperglycemic alert in lieu of the first alert when the second glucose measurement value is greater than the hyperglycemic alert threshold.

10. The method of claim 7, wherein:

determining the homeostasis metric comprises determining an estimated excess insulin amount based on the first glucose measurement value; and

automatically clearing the first alert comprises automatically clearing the first alert when the second glucose measurement value is less than a hypoglycemic alert threshold.

11. The method of claim 10, wherein automatically clearing the first alert comprises automatically providing a hypoglycemic alert in lieu of the first alert when the second glucose measurement value is less than the hypoglycemic alert threshold.

12. The method of claim 1, further comprising operating the infusion device operable to deliver a dosage of the fluid to the user based at least in part on the first value, wherein obtaining the second value comprises obtaining the second value after operating the infusion device to deliver the dosage.

13. A computer-readable medium having computer-executable instructions stored thereon that, when executed by a processing system associated with the infusion device, cause the processing system to perform the method of claim 1.

14. An infusion device comprising:

a user interface;

a motor operable to deliver fluid to a body of a user, the fluid influencing a physiological condition of the user; and

a control system coupled to the motor and the user interface to;

operate the motor to deliver the fluid;

obtain a first measurement value for the physiological condition in the body of the user;

determine a metric corresponding to a future physiological condition of the user in the future based at least in part on the first measurement value;

automatically generate a first alert via the user interface based on the metric;

obtain a second value for the physiological condition of the user after automatically generating the first alert; and

automatically clear the first alert from the user interface based at least in part on the second value.

15. The infusion device of claim 14, wherein the control system determines an updated metric corresponding to the future physiological condition of the user based at least in part on the second value and automatically clears the first alert based on the updated metric.

16. The infusion device of claim 14, wherein the control system obtains the first measurement value and the second measurement value from a sensing arrangement, the sensing arrangement sensing the physiological condition in the body of the user.

17. The infusion device of claim 14, the fluid comprising insulin influencing a glucose level in the body of the user, wherein the metric comprises a homeostasis metric indicative of the glucose level in the body of the user.

18. The infusion device of claim 14, the fluid comprising insulin influencing a glucose level in the body of the user, wherein the metric comprises a predicted value for the glucose level in the body of the user.

19. An infusion system comprising:

a user interface;

an infusion device operable to deliver fluid to a body of a user, the fluid influencing a physiological condition of the user;

a sensing arrangement to obtain measurement values for the physiological condition from the body of the user; and

a control system coupled to the user interface and the sensing arrangement to obtain a first measurement value for the physiological condition from the sensing arrangement, determine a metric corresponding to a future physiological condition of the user based at least in part on the first measurement value, automatically generate a first alert via the user interface based on the metric, and after automatically generating the first alert, obtain a second measurement value for the physiological condition from the sensing arrangement and automatically clear the first alert based at least in part on the second measurement value.

20. The infusion system of claim 19, the fluid comprising insulin influencing a glucose level in the body of the user, wherein the metric comprises a homeostasis metric indicative of the glucose level in the body of the user.