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Single-Walled Carbon Nanotube Biosensor for Detection of Glucose, Lactate, and Urea

  • US 20160178567A1
  • Filed: 08/05/2014
  • Published: 06/23/2016
  • Est. Priority Date: 08/05/2013
  • Status: Active Grant
First Claim
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1. A microscale biosensor for detecting a chemical agent, the biosensor comprising:

  • a substrate;

    a conductive layer attached to a surface of the substrate, the conductive layer forming at least one pair of electrodes with an insulating gap between the electrodes; and

    a conductive bridge consisting essentially of one or more functionalized single-walled carbon nanotubes contacting the electrodes and bridging the gap between the electrodes;

    wherein the one or more nanotubes are functionalized via a linker with an enzyme that reacts with said chemical agent, whereby the conductivity of the conductive bridge is modified; and

    wherein the linker is 1-pyrenebutanoic acid succinimidyl ester.

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