MODIFIED NUCLEOSIDES, ANALOGS THEREOF AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM
First Claim
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1. An oligomeric compound comprising at the 5′
- -position a moiety having one of the formulas;
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Abstract
The present invention provides modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom. More particularly, the present invention provides modified nucleosides and analogs thereof that are useful for incorporation at the terminus of an oligomeric compound. Such oligomeric compounds can also be included in a double stranded composition. In some embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
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20 Claims
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1. An oligomeric compound comprising at the 5′
- -position a moiety having one of the formulas;
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- -position a moiety having one of the formulas;
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13. An oligomeric compound comprising at the 5′
- -position a moiety having one of the formulas;
- View Dependent Claims (14, 15, 16, 17, 18, 19, 20)
- -position a moiety having one of the formulas;
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