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T CELL ACTIVATING BISPECIFIC ANTIGEN BINDING MOLECULES

  • US 20160208019A1
  • Filed: 11/20/2015
  • Published: 07/21/2016
  • Est. Priority Date: 11/20/2014
  • Status: Abandoned Application
First Claim
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1. A T cell activating bispecific antigen binding molecule comprising(i) a first antigen binding moiety which is a Fab molecule capable of specific binding to CD3, and which comprises at least one heavy chain complementarity determining region (CDR) amino acid sequence selected from the group consisting of SEQ ID NO:

  • 37, SEQ ID NO;

    38 and SEQ ID NO;

    39 and at least one light chain CDR selected from the group of SEQ ID NO;

    32, SEQ ID NO;

    33, SEQ ID NO;

    34;

    (ii) a second antigen binding moiety capable of specific binding to Folate Receptor 1 (FolR1).

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